Skip to main content
PMC home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1987 Aug;46(8):628–631. doi: 10.1136/ard.46.8.628

Wegener's granulomatosis: isolated involvement of the trachea and larynx.

D Hellmann 1, T Laing 1, M Petri 1, D Jacobs 1, R Crumley 1, M Stulbarg 1
PMCID: PMC1002213  PMID: 3310928

Abstract

A 26 year old man with subacute hoarseness and stridor was shown to have Wegener's granulomatosis isolated to the trachea and larynx. Although isolated laryngeal Wegener's is unusual, a review of the literature suggests that early treatment with cyclophosphamide is warranted.

Full text

PDF
628

Images in this article

628Image
on p.628

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ATKINS J. P., EISMAN S. H. Wegener's granulomatosis. Ann Otol Rhinol Laryngol. 1959 Jun;68(2):524–547. doi: 10.1177/000348945906800218. [DOI] [PubMed] [Google Scholar]
  2. Arauz J. C., Fonseca R. Wegener's granulomatosis appearing initially in the trachea. Ann Otol Rhinol Laryngol. 1982 Nov-Dec;91(6 Pt 1):593–596. doi: 10.1177/000348948209100611. [DOI] [PubMed] [Google Scholar]
  3. Carrington C. B., Liebow A. Limited forms of angiitis and granulomatosis of Wegener's type. Am J Med. 1966 Oct;41(4):497–527. doi: 10.1016/0002-9343(66)90214-2. [DOI] [PubMed] [Google Scholar]
  4. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 31-1986. A 39-year-old woman with stenosis of the subglottic area and pulmonary artery. N Engl J Med. 1986 Aug 7;315(6):378–387. doi: 10.1056/NEJM198608073150607. [DOI] [PubMed] [Google Scholar]
  5. Chizhikov V. M. Granulematoz vegenera s porazheniem zadnei stenki glotke. Vestn Otorinolaringol. 1975 Sep-Oct;(5):87–87. [PubMed] [Google Scholar]
  6. Cohen S. R., Landing B. H., King B. K., Isaacs H. Wegener's granulomatosis causing laryngeal and tracheobronchial obstruction in an adolescent girl. Ann Otol Rhinol Laryngol Suppl. 1978 Sep-Oct;87(5 Pt 2 Suppl 52):15–19. doi: 10.1177/00034894780870s504. [DOI] [PubMed] [Google Scholar]
  7. DeRemee R. A., McDonald T. J., Weiland L. H. Wegener's granulomatosis: observations on treatment with antimicrobial agents. Mayo Clin Proc. 1985 Jan;60(1):27–32. doi: 10.1016/s0025-6196(12)65279-3. [DOI] [PubMed] [Google Scholar]
  8. Fauci A. S., Haynes B. F., Katz P., Wolff S. M. Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med. 1983 Jan;98(1):76–85. doi: 10.7326/0003-4819-98-1-76. [DOI] [PubMed] [Google Scholar]
  9. GODMAN G. C., CHURG J. Wegener's granulomatosis: pathology and review of the literature. AMA Arch Pathol. 1954 Dec;58(6):533–553. [PubMed] [Google Scholar]
  10. Kornblut A. D., Wolff S. M., deFries H. O., Fauci A. S. Wegener's granulomatosis. Otolaryngol Clin North Am. 1982 Aug;15(3):673–683. [PubMed] [Google Scholar]
  11. Kurita S., Hirano M. Wegener's granuloma localized in the larynx. Report of a case. Auris Nasus Larynx. 1983;10 (Suppl):S97–104. doi: 10.1016/s0385-8146(83)80011-x. [DOI] [PubMed] [Google Scholar]
  12. Lampman J. H., Querubin R., Kondapalli P. Subglottic stenosis in Wegener's granulomatosis. Chest. 1981 Feb;79(2):230–232. doi: 10.1378/chest.79.2.230. [DOI] [PubMed] [Google Scholar]
  13. McDonald T. J., Neel H. B., 3rd, DeRemee R. A. Wegener's granulomatosis of the subglottis and the upper portion of the trachea. Ann Otol Rhinol Laryngol. 1982 Nov-Dec;91(6 Pt 1):588–592. doi: 10.1177/000348948209100610. [DOI] [PubMed] [Google Scholar]
  14. STRATTON H. J. M., PRICE T. M. L., SKELTON M. O. Granuloma of the nose and periarteritis nodosa. Br Med J. 1953 Jan 17;1(4802):127–130. doi: 10.1136/bmj.1.4802.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Shah I. A., Holstege A., Riede U. N. Bioptic diagnosis of Wegener's granulomatosis in the absence of vasculitis and granulomas. Pathol Res Pract. 1984 Mar;178(4):407–415. doi: 10.1016/S0344-0338(84)80042-4. [DOI] [PubMed] [Google Scholar]
  16. Talerman A., Wright D. Laryngeal obstruction due to Wegener's granulomatosis. Arch Otolaryngol. 1972 Oct;96(4):376–379. doi: 10.1001/archotol.1972.00770090552016. [DOI] [PubMed] [Google Scholar]
  17. Terent A., Wibell L., Lindholm C. E., Wilbrand H. Laryngeal granuloma in the early stages of Wegener's granulomatosis. ORL J Otorhinolaryngol Relat Spec. 1980;42(5):258–265. doi: 10.1159/000275504. [DOI] [PubMed] [Google Scholar]
  18. WALTON E. W. Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis). Br Med J. 1958 Aug 2;2(5091):265–270. doi: 10.1136/bmj.2.5091.265. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES