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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1987 Sep;46(9):674–680. doi: 10.1136/ard.46.9.674

Standardisation of serological tests for rheumatoid factor measurement.

F Klein 1, M B Janssens 1
PMCID: PMC1002231  PMID: 3499874

Abstract

Standardisation of quantitative data obtained by several types of rheumatoid factor test was achieved by the use of a reference serum preparation. Interlaboratory comparability improved for the latex fixation test, the Waaler-Rose test, the IgM RF test by an enzyme linked immunosorbent assay (ELISA), and for the antiperinuclear factor test. Use of a common method and latex preparation was not sufficient to improve comparability for the latex test. The comparability of IgM RF tests by immunofluorescence (IF) was not changed by reading against a common reference. It is concluded that expression in international units, as defined by the World Health Organisation (WHO), improves interlaboratory comparison of quantitative data in rheumatoid serology.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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