Abstract
Professional experience and lay wisdom teach us the benefits of exercise and the hazards of idleness. Yet the myth persists that "bed rest is good for you" when ill or convalescing. Abundant scientific evidence in the past 50 years has demonstrated the specific damage done to each of the body's organ systems by inactivity. Both aging and inactivity lead to strikingly similar kinds of deterioration. I summarize the data from military and veterans' hospitals, rehabilitation experience, aerospace research, and gerontology and review the physiologic and metabolic changes of aging and inactivity, along with strategies to help prevent the iatrogenic complications of bed rest.
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Selected References
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- ASHER R. A. J. The dangers of going to bed. Br Med J. 1947 Dec 13;2(4536):967–967. doi: 10.1136/bmj.2.4536.967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bortz W. M., 2nd Disuse and aging. JAMA. 1982 Sep 10;248(10):1203–1208. [PubMed] [Google Scholar]
- Frontera W. R., Meredith C. N., O'Reilly K. P., Knuttgen H. G., Evans W. J. Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol (1985) 1988 Mar;64(3):1038–1044. doi: 10.1152/jappl.1988.64.3.1038. [DOI] [PubMed] [Google Scholar]
- Harper C. M., Lyles Y. M. Physiology and complications of bed rest. J Am Geriatr Soc. 1988 Nov;36(11):1047–1054. doi: 10.1111/j.1532-5415.1988.tb04375.x. [DOI] [PubMed] [Google Scholar]
- Page N. Weightlessness: a matter of gravity. N Engl J Med. 1977 Jul 7;297(1):32–37. doi: 10.1056/NEJM197707072970106. [DOI] [PubMed] [Google Scholar]
- Ryback R. S., Trimble R. W., Lewis O. F., Jennings C. L. Psychobiologic effects of prolonged weightlessness (bed rest) in young healthy volunteers. Aerosp Med. 1971 Apr;42(4):408–415. [PubMed] [Google Scholar]
- ZUBEK J. P. COUNTERACTING EFFECTS OF PHYSICAL EXERCISES PERFORMED DURING PROLONGED PERCEPTUAL DEPRIVATION. Science. 1963 Oct 25;142(3591):504–506. doi: 10.1126/science.142.3591.504. [DOI] [PubMed] [Google Scholar]