Skip to main content
NCBI home page
The Western Journal of Medicine logoLink to The Western Journal of Medicine
. 1991 May;154(5):549–553.

Human immunodeficiency virus infection and diffuse polyneuropathy. Implications for rehabilitation medicine.

J A Mukand 1
PMCID: PMC1002826  PMID: 1866948

Abstract

Patients at various stages of human immunodeficiency virus (HIV) infection require rehabilitation services. These patients present problems for each of the disciplines in a rehabilitation team, and all team members must confront the psychosocial and ethical issues involved with the disease. Patients with HIV infection may have polyneuropathy with multisystem involvement, including dysphagia, autonomic dysfunction, respiratory failure, bowel and bladder dysfunction, generalized weakness, a painful sensory neuropathy, and depression. Guidelines are presented for determining if inpatient rehabilitation or other settings are appropriate. Case management is a valuable strategy for the rehabilitation of patients with this complicated disorder.

Full text

PDF
549

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abrams D. I., Dilley J. W., Maxey L. M., Volberding P. A. Routine care and psychosocial support of the patient with the acquired immunodeficiency syndrome. Med Clin North Am. 1986 May;70(3):707–720. doi: 10.1016/s0025-7125(16)30948-8. [DOI] [PubMed] [Google Scholar]
  2. Bacchetti P., Moss A. R. Incubation period of AIDS in San Francisco. Nature. 1989 Mar 16;338(6212):251–253. doi: 10.1038/338251a0. [DOI] [PubMed] [Google Scholar]
  3. Chin J., Mann J. Global surveillance and forecasting of AIDS. Bull World Health Organ. 1989;67(1):1–7. [PMC free article] [PubMed] [Google Scholar]
  4. Cornblath D. R., McArthur J. C., Kennedy P. G., Witte A. S., Griffin J. W. Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus type III infection. Ann Neurol. 1987 Jan;21(1):32–40. doi: 10.1002/ana.410210107. [DOI] [PubMed] [Google Scholar]
  5. Dalakas M. C., Pezeshkpour G. H., Gravell M., Sever J. L. Polymyositis associated with AIDS retrovirus. JAMA. 1986 Nov 7;256(17):2381–2383. [PubMed] [Google Scholar]
  6. Dalakas M., Wichman A., Sever J. AIDS and the nervous system. JAMA. 1989 Apr 28;261(16):2396–2399. [PubMed] [Google Scholar]
  7. Dilley J. W., Ochitill H. N., Perl M., Volberding P. A. Findings in psychiatric consultations with patients with acquired immune deficiency syndrome. Am J Psychiatry. 1985 Jan;142(1):82–86. doi: 10.1176/ajp.142.1.82. [DOI] [PubMed] [Google Scholar]
  8. Goudsmit J., Wolters E. C., Bakker M., Smit L., Van der Noordaa J., Hische E. A., Tutuarima J. A., Van der Helm H. J. Intrathecal synthesis of antibodies to HTLV-III in patients without AIDS or AIDS related complex. Br Med J (Clin Res Ed) 1986 May 10;292(6530):1231–1234. doi: 10.1136/bmj.292.6530.1231. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ho D. D., Rota T. R., Schooley R. T., Kaplan J. C., Allan J. D., Groopman J. E., Resnick L., Felsenstein D., Andrews C. A., Hirsch M. S. Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med. 1985 Dec 12;313(24):1493–1497. doi: 10.1056/NEJM198512123132401. [DOI] [PubMed] [Google Scholar]
  10. King A. C., Taylor C. B., Haskell W. L., Debusk R. F. Strategies for increasing early adherence to and long-term maintenance of home-based exercise training in healthy middle-aged men and women. Am J Cardiol. 1988 Mar 1;61(8):628–632. doi: 10.1016/0002-9149(88)90778-3. [DOI] [PubMed] [Google Scholar]
  11. Levy R. M., Bredesen D. E., Rosenblum M. L. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg. 1985 Apr;62(4):475–495. doi: 10.3171/jns.1985.62.4.0475. [DOI] [PubMed] [Google Scholar]
  12. Lipkin W. I., Parry G., Kiprov D., Abrams D. Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology. 1985 Oct;35(10):1479–1483. doi: 10.1212/wnl.35.10.1479. [DOI] [PubMed] [Google Scholar]
  13. Make B. J. Pulmonary rehabilitation: myth or reality? Clin Chest Med. 1986 Dec;7(4):519–540. [PubMed] [Google Scholar]
  14. Marcusen D. C., Sooy C. D. Otolaryngologic and head and neck manifestations of acquired immunodeficiency syndrome (AIDS). Laryngoscope. 1985 Apr;95(4):401–405. doi: 10.1288/00005537-198504000-00006. [DOI] [PubMed] [Google Scholar]
  15. McArthur J. H., McArthur J. C. Neurological manifestations of acquired immunodeficiency syndrome. J Neurosci Nurs. 1986 Oct;18(5):242–249. doi: 10.1097/01376517-198610000-00002. [DOI] [PubMed] [Google Scholar]
  16. Merigan T. C., Skowron G., Bozzette S. A., Richman D., Uttamchandani R., Fischl M., Schooley R., Hirsch M., Soo W., Pettinelli C. Circulating p24 antigen levels and responses to dideoxycytidine in human immunodeficiency virus (HIV) infections. A phase I and II study. Ann Intern Med. 1989 Feb 1;110(3):189–194. doi: 10.7326/0003-4819-110-3-189. [DOI] [PubMed] [Google Scholar]
  17. Meythaler J. M., Cross L. L. Traumatic spinal cord injury complicated by AIDS related complex. Arch Phys Med Rehabil. 1988 Mar;69(3 Pt 1):219–222. [PubMed] [Google Scholar]
  18. Molina J. M., Groopman J. E. Bone marrow toxicity of dideoxyinosine. N Engl J Med. 1989 Nov 23;321(21):1478–1478. doi: 10.1056/NEJM198911233212113. [DOI] [PubMed] [Google Scholar]
  19. Navia B. A., Jordan B. D., Price R. W. The AIDS dementia complex: I. Clinical features. Ann Neurol. 1986 Jun;19(6):517–524. doi: 10.1002/ana.410190602. [DOI] [PubMed] [Google Scholar]
  20. Navia B. A., Price R. W. The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection. Arch Neurol. 1987 Jan;44(1):65–69. doi: 10.1001/archneur.1987.00520130051017. [DOI] [PubMed] [Google Scholar]
  21. Perry S., Jacobsen P. Neuropsychiatric manifestations of AIDS-spectrum disorders. Hosp Community Psychiatry. 1986 Feb;37(2):135–142. doi: 10.1176/ps.37.2.135. [DOI] [PubMed] [Google Scholar]
  22. Petito C. K., Navia B. A., Cho E. S., Jordan B. D., George D. C., Price R. W. Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1985 Apr 4;312(14):874–879. doi: 10.1056/NEJM198504043121402. [DOI] [PubMed] [Google Scholar]
  23. Resnick L., diMarzo-Veronese F., Schüpbach J., Tourtellotte W. W., Ho D. D., Müller F., Shapshak P., Vogt M., Groopman J. E., Markham P. D. Intra-blood-brain-barrier synthesis of HTLV-III-specific IgG in patients with neurologic symptoms associated with AIDS or AIDS-related complex. N Engl J Med. 1985 Dec 12;313(24):1498–1504. doi: 10.1056/NEJM198512123132402. [DOI] [PubMed] [Google Scholar]
  24. Scheinberg L., Smith C. R. Rehabilitation of patients with multiple sclerosis. Neurol Clin. 1987 Nov;5(4):585–600. [PubMed] [Google Scholar]
  25. Shaw G. M., Harper M. E., Hahn B. H., Epstein L. G., Gajdusek D. C., Price R. W., Navia B. A., Petito C. K., O'Hara C. J., Groopman J. E. HTLV-III infection in brains of children and adults with AIDS encephalopathy. Science. 1985 Jan 11;227(4683):177–182. doi: 10.1126/science.2981429. [DOI] [PubMed] [Google Scholar]
  26. Snider W. D., Simpson D. M., Nielsen S., Gold J. W., Metroka C. E., Posner J. B. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol. 1983 Oct;14(4):403–418. doi: 10.1002/ana.410140404. [DOI] [PubMed] [Google Scholar]
  27. Vendrell J., Heredia C., Pujol M., Vidal J., Blesa R., Graus F. Guillain-Barré syndrome associated with seroconversion for anti-HTLV-III. Neurology. 1987 Mar;37(3):544–544. doi: 10.1212/wnl.37.3.544-a. [DOI] [PubMed] [Google Scholar]
  28. Yankner B. A., Skolnik P. R., Shoukimas G. M., Gabuzda D. H., Sobel R. A., Ho D. D. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Ann Neurol. 1986 Sep;20(3):362–364. doi: 10.1002/ana.410200316. [DOI] [PubMed] [Google Scholar]

Articles from Western Journal of Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES