Abstract
The Alaska Department of Health and Social Services investigated a community outbreak of hepatitis A in Anchorage. A total of 57 persons who had hepatitis A between June and September 1988 were studied. Patients ranged from 1 to 54 years of age. A market was implicated as the source of the outbreak. An employee who prepared beverage mixtures in a bathroom was a contact of a person who had had hepatitis A 2 months before the outbreak; the employee was reported to have been jaundiced 3 to 4 weeks before the peak of the outbreak. The administration of immune globulin had an efficacy of 100% (95% confidence limits 69, 100%) in preventing hepatitis A among household contacts of primary cases. Similar beverages are sold by convenience markets and many other businesses nationwide. It is important to ensure that safe food-handling practices are followed by such establishments.
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Selected References
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- ASHLEY A. Gamma globulin; effect on secondary attack rates in infectious hepatitis. N Engl J Med. 1954 Mar 11;250(10):412–417. doi: 10.1056/NEJM195403112501003. [DOI] [PubMed] [Google Scholar]
- BROOKS B. F., HSIA D. Y., GELLIS S. S. Family outbreaks of infectious hepatitis; prophylactic use of gamma globulin. N Engl J Med. 1953 Jul 9;249(2):58–61. doi: 10.1056/NEJM195307092490202. [DOI] [PubMed] [Google Scholar]
- Bowen G. S., McCarthy M. A. Hepatitis A associated with a hardware store water fountain and a contaminated well in Lancaster County, Pennsylvania, 1980. Am J Epidemiol. 1983 Jun;117(6):695–705. doi: 10.1093/oxfordjournals.aje.a113603. [DOI] [PubMed] [Google Scholar]
- HSIA D. Y., LONSWAY M., Jr, GELLIS S. S. Gamma globulin in the prevention of infectious hepatitis; studies on the use of small doses in family outbreaks. N Engl J Med. 1954 Mar 11;250(10):417–419. doi: 10.1056/NEJM195403112501004. [DOI] [PubMed] [Google Scholar]
- Landrigan P. J., Huber D. H., Murphy G. D., 3rd, Creech W. B., Bryan J. A. The protective efficacy of immune serum globulin in hepatitis A: a statistical approach. JAMA. 1973 Jan 1;223(1):74–75. [PubMed] [Google Scholar]
- NOBLE H. B., PETERSON D. R. EVALUATION OF IMMUNE SERUM GLOBULIN FOR CONTROL OF INFECTIOUS HEPATITIS. Public Health Rep. 1965 Feb;80:173–177. [PMC free article] [PubMed] [Google Scholar]
- Orenstein W. A., Bernier R. H., Dondero T. J., Hinman A. R., Marks J. S., Bart K. J., Sirotkin B. Field evaluation of vaccine efficacy. Bull World Health Organ. 1985;63(6):1055–1068. [PMC free article] [PubMed] [Google Scholar]
- Storch G., McFarland L. M., Kelso K., Heilman C. J., Caraway C. T. Viral hepatitis associated with day-care centers. JAMA. 1979 Oct 5;242(14):1514–1518. [PubMed] [Google Scholar]