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. 1988 Jan;47(1):40–42. doi: 10.1136/ard.47.1.40

Comparison of sleep in osteoarthritic patients and age and sex matched healthy controls.

T J Leigh 1, I Hindmarch 1, H A Bird 1, V Wright 1
PMCID: PMC1003441  PMID: 3345103

Abstract

A sleep laboratory comparison of the sleep of 14 osteoarthritic patients with that of 16 age and sex matched healthy controls was undertaken. After three nights of adaptation continuous recordings of electroencephalographic (EEG), electro-oculographic (EOG), and electromyographic (EMG) activity were obtained for the next two nights. A comparison of EEG sleep variables during this baseline period showed that osteoarthritic patients had a significantly greater percentage of stage 1 and significantly smaller percentage of stage 2 sleep than control subjects. These findings indicate sleep disturbance in osteoarthritic patients. The limited degree of disturbance observed in these patients may be due to the fact that they were allowed to continue with their normal anti-inflammatory and analgesic medication for the course of the study.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agnew H. W., Jr, Webb W. B., Williams R. L. The first night effect: an EEG study of sleep. Psychophysiology. 1966 Jan;2(3):263–266. doi: 10.1111/j.1469-8986.1966.tb02650.x. [DOI] [PubMed] [Google Scholar]
  2. Bayley T. R., Haslock I. Night medication in rheumatoid arthritis. J R Coll Gen Pract. 1976 Aug;26(169):591–594. [PMC free article] [PubMed] [Google Scholar]
  3. Brezinova V., Catterall J. R., Douglas N. J., Calverley P. M., Flenley D. C. Night sleep of patients with chronic ventilatory failure and age matched controls: number and duration of the EEG episodes of intervening wakefulness and drowsiness. Sleep. 1982;5(2):123–130. doi: 10.1093/sleep/5.2.123. [DOI] [PubMed] [Google Scholar]
  4. Cohen L. A controlled study of Trancopal in sleep disturbances due to rheumatic disease. J Int Med Res. 1978;6(2):111–114. doi: 10.1177/030006057800600207. [DOI] [PubMed] [Google Scholar]
  5. Condie R. Chlormezanone in the treatment of insomnia due to rheumatic stiffness. Curr Med Res Opin. 1979;6(3):217–220. doi: 10.1185/03007997909109426. [DOI] [PubMed] [Google Scholar]
  6. Frankel B. L., Coursey R. D., Buchbinder R., Snyder F. Recorded and reported sleep in chronic primary insomnia. Arch Gen Psychiatry. 1976 May;33(5):615–623. doi: 10.1001/archpsyc.1976.01770050067011. [DOI] [PubMed] [Google Scholar]
  7. Gerard P., Collins K. J., Dore C., Exton-Smith A. N. Subjective characteristics of sleep in the elderly. Age Ageing. 1978;Suppl:55–63. doi: 10.1093/ageing/7.suppl.55. [DOI] [PubMed] [Google Scholar]
  8. Kales A., Beall G. N., Bajor G. F., Jacobson A., Kales J. D. Sleep studies in asthmatic adults: relationship of attacks to sleep stage and time of night. J Allergy. 1968 Mar;41(3):164–173. doi: 10.1016/0021-8707(68)90056-7. [DOI] [PubMed] [Google Scholar]
  9. Karacan I., Williams R. L., Taylor W. J. Sleep characteristics of patients with angina pectoris. Psychosomatics. 1969 Sep-Oct;10(5):280–284. doi: 10.1016/S0033-3182(69)71713-3. [DOI] [PubMed] [Google Scholar]
  10. Moldofsky H., Scarisbrick P., England R., Smythe H. Musculosketal symptoms and non-REM sleep disturbance in patients with "fibrositis syndrome" and healthy subjects. Psychosom Med. 1975 Jul-Aug;37(4):341–351. doi: 10.1097/00006842-197507000-00008. [DOI] [PubMed] [Google Scholar]
  11. Oswald I. Sleep studies in clinical pharmacology. Br J Clin Pharmacol. 1980 Oct;10(4):317–326. doi: 10.1111/j.1365-2125.1980.tb01767.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Williams R. L., Karacan I., Thornby J. I., Salis P. J. The electroencephalogram sleep patterns of middle-aged males. J Nerv Ment Dis. 1972 Jan;154(1):22–30. doi: 10.1097/00005053-197201000-00004. [DOI] [PubMed] [Google Scholar]
  13. Wojtulewski J. A., Walter J. Treatment of sleep disturbance in arthritis with chlormezanone. Curr Med Res Opin. 1983;8(7):456–460. doi: 10.1185/03007998309109782. [DOI] [PubMed] [Google Scholar]

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