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. 1988 Oct;47(10):793–796. doi: 10.1136/ard.47.10.793

Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in patients with rheumatoid arthritis.

M Magaro 1, L Altomonte 1, A Zoli 1, L Mirone 1, P De Sole 1, G Di Mario 1, S Lippa 1, A Oradei 1
PMCID: PMC1003605  PMID: 3196080

Abstract

Neutrophil chemiluminescence was determined in patients with active rheumatoid arthritis. Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids. A correlation with clinical and laboratory parameters is also reported. No statistical difference was observed in neutrophil chemiluminescence and in clinical parameters in the group of patients treated with a diet high in saturated fatty acids. Fish oil ingestion resulted in subjective alleviation of active rheumatoid arthritis and reduction of neutrophil chemiluminescence. This study corroborates the hypothesis of an anti-inflammatory role for polyunsaturated fatty acids in patients with chronic inflammatory diseases.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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