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. 1989 Mar;48(3):232–235. doi: 10.1136/ard.48.3.232

Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies.

R A Asherson 1, J Zulman 1, G R Hughes 1
PMCID: PMC1003727  PMID: 2494958

Abstract

Procainamide is the commonest cause of a drug induced lupus syndrome. Long term administration of this compound may induce a variety of immunological abnormalities, including antinuclear antibodies. Uncommonly, 'lupus anticoagulants' have been demonstrated in the absence of other evidence of drug induced lupus. Details of a 67 year old man who developed not only drug induced lupus but also antiphospholipid antibodies which were associated with multiple pulmonary thromboemboli after the administration of procainamide are recorded.

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Selected References

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