Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1989 Aug;48(8):683–685. doi: 10.1136/ard.48.8.683

Auricular chondritis and diffuse proliferative glomerulonephritis in primary Sjögren's syndrome.

M A Rodriguez 1, F J Tapanes 1, I L Stekman 1, J A Pinto 1, O Camejo 1, I Abadi 1
PMCID: PMC1003847  PMID: 2782978

Abstract

Bilateral auricular inflammation with histological changes of relapsing polychondritis was observed in a female patient with primary Sjögren's syndrome. This was accompanied by rapidly progressive renal insufficiency due to diffuse proliferative glomerulonephritis. To our knowledge this is the first well documented case of primary Sjögren's syndrome associated with chondritis and glomerulonephritis, further emphasising the wide spectrum of extraglandular manifestations in this autoimmune disorder.

Full text

PDF
683

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander E. L., Malinow K., Lejewski J. E., Jerdan M. S., Provost T. T., Alexander G. E. Primary Sjögren's syndrome with central nervous system disease mimicking multiple sclerosis. Ann Intern Med. 1986 Mar;104(3):323–330. doi: 10.7326/0003-4819-104-3-323. [DOI] [PubMed] [Google Scholar]
  2. Balow J. E., Austin H. A., 3rd, Tsokos G. C., Antonovych T. T., Steinberg A. D., Klippel J. H. NIH conference. Lupus nephritis. Ann Intern Med. 1987 Jan;106(1):79–94. doi: 10.7326/0003-4819-106-1-79. [DOI] [PubMed] [Google Scholar]
  3. Foidart J. M., Abe S., Martin G. R., Zizic T. M., Barnett E. V., Lawley T. J., Katz S. I. Antibodies to type II collagen in relapsing polychondritis. N Engl J Med. 1978 Nov 30;299(22):1203–1207. doi: 10.1056/NEJM197811302992202. [DOI] [PubMed] [Google Scholar]
  4. Fox R. I., Howell F. V., Bone R. C., Michelson P. Primary Sjogren syndrome: clinical and immunopathologic features. Semin Arthritis Rheum. 1984 Nov;14(2):77–105. doi: 10.1016/0049-0172(84)90001-5. [DOI] [PubMed] [Google Scholar]
  5. Fox R. I., Robinson C. A., Curd J. G., Kozin F., Howell F. V. Sjögren's syndrome. Proposed criteria for classification. Arthritis Rheum. 1986 May;29(5):577–585. doi: 10.1002/art.1780290501. [DOI] [PubMed] [Google Scholar]
  6. Hughes R. A., Berry C. L., Seifert M., Lessof M. H. Relapsing polychondritis. Three cases with a clinico-pathological study and literature review. Q J Med. 1972 Jul;41(163):363–380. [PubMed] [Google Scholar]
  7. Levinson A. I., Dziarski A., Pincus T., deHoratius R. J., Zweiman B. Heterogeneity of polyclonal B-cell activity in systemic lupus erythematosus. J Clin Lab Immunol. 1981 Jan;5(1):17–22. [PubMed] [Google Scholar]
  8. McAdam L. P., O'Hanlan M. A., Bluestone R., Pearson C. M. Relapsing polychondritis: prospective study of 23 patients and a review of the literature. Medicine (Baltimore) 1976 May;55(3):193–215. [PubMed] [Google Scholar]
  9. Moutsopoulos H. M., Balow J. E., Lawley T. J., Stahl N. I., Antonovych T. T., Chused T. M. Immune complex glomerulonephritis in sicca syndrome. Am J Med. 1978 Jun;64(6):955–960. doi: 10.1016/0002-9343(78)90449-7. [DOI] [PubMed] [Google Scholar]
  10. Neild G. H., Cameron J. S., Lessof M. H., Ogg C. S., Turner D. R. Relapsing polychondritis with crescentic glomerulonephritis. Br Med J. 1978 Mar 25;1(6115):743–745. doi: 10.1136/bmj.1.6115.743. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Okudaira K., Tanimoto K., Nakamura T., Horiuchi Y. Spontaneously enhanced in vitro immunoglobulin synthesis by B cells in systemic lupus erythematosus. Clin Immunol Immunopathol. 1980 Jul;16(3):267–278. doi: 10.1016/0090-1229(80)90132-4. [DOI] [PubMed] [Google Scholar]
  12. Rodriguez M. A., Baroja M. L., Leon-Ponte M., Abadi I. Abnormal immunoglobulin and rheumatoid factor synthesis by blood lymphocytes in patients with primary Sjögren's syndrome. Arthritis Rheum. 1986 Dec;29(12):1446–1455. doi: 10.1002/art.1780291205. [DOI] [PubMed] [Google Scholar]
  13. Ruhlen J. L., Huston K. A., Wood W. G. Relapsing polychondritis with glomerulonephritis. Improvement with prednisone and cyclophosphamide. JAMA. 1981 Feb 27;245(8):847–848. [PubMed] [Google Scholar]
  14. Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES