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. 1990 Oct;49(10):779–782. doi: 10.1136/ard.49.10.779

A prospective study on antiribosomal P proteins in two cases of familial lupus and recurrent psychosis.

R H Derksen 1, A P van Dam 1, F H Gmelig Meyling 1, J W Bijlsma 1, R J Smeenk 1
PMCID: PMC1004231  PMID: 2241267

Abstract

In two siblings with systemic lupus erythematosus (SLE), who experienced two episodes of psychosis each, a longitudinal study of autoantibodies, including antibodies to ribosomal P proteins, is described. In two of three evaluable periods of 15 weeks antedating psychosis a rise followed by a spontaneous drop in anti-P levels was recorded. In the third period antibodies to ribosomal protein P were absent. It is concluded that results with single samples are not informative, and that frequent measurement of antibodies to ribosomal protein P in patients with SLE may have limited predictive value for psychosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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