Skip to main content
PMC home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1990 Dec;49(12):961–965. doi: 10.1136/ard.49.12.961

Autoantibodies and antibacterial antibodies: from both sides now.

R A Watts 1, D A Isenberg 1
PMCID: PMC1004284  PMID: 2270967

Full text

PDF
961

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Atkinson P. M., Lampman G. W., Furie B. C., Naparstek Y., Schwartz R. S., Stollar B. D., Furie B. Homology of the NH2-terminal amino acid sequences of the heavy and light chains of human monoclonal lupus autoantibodies containing the dominant 16/6 idiotype. J Clin Invest. 1985 Apr;75(4):1138–1143. doi: 10.1172/JCI111808. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Avrameas S., Guilbert B., Mahana W., Matsiota P., Ternynck T. Recognition of self and non-self constituents by polyspecific autoreceptors. Int Rev Immunol. 1988 Mar;3(1-2):1–15. doi: 10.3109/08830188809051179. [DOI] [PubMed] [Google Scholar]
  3. Burastero S. E., Casali P., Wilder R. L., Notkins A. L. Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis. J Exp Med. 1988 Dec 1;168(6):1979–1992. doi: 10.1084/jem.168.6.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cairns E., Block J., Bell D. A. Anti-DNA autoantibody-producing hybridomas of normal human lymphoid cell origin. J Clin Invest. 1984 Sep;74(3):880–887. doi: 10.1172/JCI111505. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Cairns E., Massicotte H., Bell D. A. Expression in systemic lupus erythematosus of an idiotype common to DNA-binding and nonbinding monoclonal antibodies produced by normal human lymphoid cells. J Clin Invest. 1989 Mar;83(3):1002–1009. doi: 10.1172/JCI113941. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Carroll P., Stafford D., Schwartz R. S., Stollar B. D. Murine monoclonal anti-DNA autoantibodies bind to endogenous bacteria. J Immunol. 1985 Aug;135(2):1086–1090. [PubMed] [Google Scholar]
  7. Casali P., Burastero S. E., Nakamura M., Inghirami G., Notkins A. L. Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset. Science. 1987 Apr 3;236(4797):77–81. doi: 10.1126/science.3105056. [DOI] [PubMed] [Google Scholar]
  8. Casali P., Notkins A. L. CD5+ B lymphocytes, polyreactive antibodies and the human B-cell repertoire. Immunol Today. 1989 Nov;10(11):364–368. doi: 10.1016/0167-5699(89)90268-5. [DOI] [PubMed] [Google Scholar]
  9. Conger J. D., Pike B. L., Nossal G. J. Clonal analysis of the anti-DNA repertoire of murine B lymphocytes. Proc Natl Acad Sci U S A. 1987 May;84(9):2931–2935. doi: 10.1073/pnas.84.9.2931. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Crowley J. J., Goldfien R. D., Schrohenloher R. E., Spiegelberg H. L., Silverman G. J., Mageed R. A., Jefferis R., Koopman W. J., Carson D. A., Fong S. Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteins. J Immunol. 1988 May 15;140(10):3411–3418. [PubMed] [Google Scholar]
  11. Dar O., Salaman M. R., Seifert M. H., Isenberg D. A. B lymphocyte activation in systemic lupus erythematosus: spontaneous production of IgG antibodies to DNA and environmental antigens in cultures of blood mononuclear cells. Clin Exp Immunol. 1988 Sep;73(3):430–435. [PMC free article] [PubMed] [Google Scholar]
  12. Dauphinée M., Tovar Z., Talal N. B cells expressing CD5 are increased in Sjögren's syndrome. Arthritis Rheum. 1988 May;31(5):642–647. doi: 10.1002/art.1780310509. [DOI] [PubMed] [Google Scholar]
  13. Davidson A., Preud'homme J. L., Solomon A., Chang M. D., Beede S., Diamond B. Idiotypic analysis of myeloma proteins: anti-DNA activity of monoclonal immunoglobulins bearing an SLE idiotype is more common in IgG than IgM antibodies. J Immunol. 1987 Mar 1;138(5):1515–1518. [PubMed] [Google Scholar]
  14. Dersimonian H., McAdam K. P., Mackworth-Young C., Stollar B. D. The recurrent expression of variable region segments in human IgM anti-DNA autoantibodies. J Immunol. 1989 Jun 1;142(11):4027–4033. [PubMed] [Google Scholar]
  15. Dersimonian H., Schwartz R. S., Barrett K. J., Stollar B. D. Relationship of human variable region heavy chain germ-line genes to genes encoding anti-DNA autoantibodies. J Immunol. 1987 Oct 1;139(7):2496–2501. [PubMed] [Google Scholar]
  16. Devey M. E., Lee S. R., Le Page S., Feldman R., Isenberg D. A. Serial studies of the IgG subclass and functional affinity of DNA antibodies in systemic lupus erythematosus. J Autoimmun. 1988 Oct;1(5):483–494. doi: 10.1016/0896-8411(88)90069-8. [DOI] [PubMed] [Google Scholar]
  17. Diamond B., Scharff M. D. Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci U S A. 1984 Sep;81(18):5841–5844. doi: 10.1073/pnas.81.18.5841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Dighiero G., Guilbert B., Fermand J. P., Lymberi P., Danon F., Avrameas S. Thirty-six human monoclonal immunoglobulins with antibody activity against cytoskeleton proteins, thyroglobulin, and native DNA: immunologic studies and clinical correlations. Blood. 1983 Aug;62(2):264–270. [PubMed] [Google Scholar]
  19. Eilat D., Webster D. M., Rees A. R. V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice. J Immunol. 1988 Sep 1;141(5):1745–1753. [PubMed] [Google Scholar]
  20. Guilbert B., Dighiero G., Avrameas S. Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. J Immunol. 1982 Jun;128(6):2779–2787. [PubMed] [Google Scholar]
  21. Hardy R. R., Hayakawa K., Shimizu M., Yamasaki K., Kishimoto T. Rheumatoid factor secretion from human Leu-1+ B cells. Science. 1987 Apr 3;236(4797):81–83. doi: 10.1126/science.3105057. [DOI] [PubMed] [Google Scholar]
  22. Harkiss G. D., Hendrie F. M., Thompson D. Anti-Klebsiella K30 phospholipid antibodies in systemic lupus erythematosus: antigen cross-reactions and idiotypic sharing with antibodies to DNA and Klebsiella K30 polysaccharide. J Clin Immunol. 1988 Jul;8(4):319–331. doi: 10.1007/BF00916560. [DOI] [PubMed] [Google Scholar]
  23. Hoch S., Schur P. H., Schwaber J. Frequency of anti-DNA antibody producing cells from normals and patients with systemic lupus erythematosus. Clin Immunol Immunopathol. 1983 Apr;27(1):28–37. doi: 10.1016/0090-1229(83)90053-3. [DOI] [PubMed] [Google Scholar]
  24. Hoch S., Schwaber J. Identification and sequence of the VH gene elements encoding a human anti-DNA antibody. J Immunol. 1987 Sep 1;139(5):1689–1693. [PubMed] [Google Scholar]
  25. Holmberg D., Andersson A., Carlsson L., Forsgren S. Establishment and functional implications of B-cell connectivity. Immunol Rev. 1989 Aug;110:89–103. doi: 10.1111/j.1600-065x.1989.tb00028.x. [DOI] [PubMed] [Google Scholar]
  26. Isenberg D. A., Feldman R., Dudeney C., Konikoff F., Jones D., Ebringer A., Shoenfeld Y. A study of antipolynucleotide antibodies, anti-Klebsiella (K30) antibodies and anti-DNA antibody idiotypes in ankylosing spondylitis. Br J Rheumatol. 1987 Jun;26(3):168–171. doi: 10.1093/rheumatology/26.3.168. [DOI] [PubMed] [Google Scholar]
  27. Isenberg D. A., Shoenfeld Y., Madaio M. P., Rauch J., Reichlin M., Stollar B. D., Schwartz R. S. Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet. 1984 Aug 25;2(8400):417–422. doi: 10.1016/s0140-6736(84)92904-0. [DOI] [PubMed] [Google Scholar]
  28. KRITZMAN J., KUNKEL H. G., MCCARTHY J., MELLORS R. C. Studies of a Waldenstrom-type macroglobulin with rheumatoid factor properties. J Lab Clin Med. 1961 Jun;57:905–917. [PubMed] [Google Scholar]
  29. Kabat E. A., Nickerson K. G., Liao J., Grossbard L., Osserman E. F., Glickman E., Chess L., Robbins J. B., Schneerson R., Yang Y. H. A human monoclonal macroglobulin with specificity for alpha(2----8)-linked poly-N-acetyl neuraminic acid, the capsular polysaccharide of group B meningococci and Escherichia coli K1, which crossreacts with polynucleotides and with denatured DNA. J Exp Med. 1986 Aug 1;164(2):642–654. doi: 10.1084/jem.164.2.642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Lampman G. W., Furie B., Schwartz R. S., Stollar B. D., Furie B. C. Amino acid sequence of a platelet-binding human anti-DNA monoclonal autoantibody. Blood. 1989 Jul;74(1):262–269. [PubMed] [Google Scholar]
  31. Lindqvist K. J., Coleman R. E., Osterland C. K. Autoantibodies in chronic pulmonary tuberculosis. J Chronic Dis. 1970 Apr;22(11):717–725. doi: 10.1016/0021-9681(70)90047-0. [DOI] [PubMed] [Google Scholar]
  32. Locniskar M., Zumla A., Mudd D. W., Isenberg D. A., Williams W., McAdam K. P. Human monoclonal antibodies to phenolic glycolipid-I derived from patients with leprosy, and production of specific anti-idiotypes. Immunology. 1988 Jun;64(2):245–251. [PMC free article] [PubMed] [Google Scholar]
  33. Lydyard P. M., Quartey-Papafio R., Bröker B., Mackenzie L., Jouquan J., Blaschek M. A., Steele J., Petrou M., Collins P., Isenberg D. The antibody repertoire of early human B cells. I. High frequency of autoreactivity and polyreactivity. Scand J Immunol. 1990 Jan;31(1):33–43. doi: 10.1111/j.1365-3083.1990.tb02740.x. [DOI] [PubMed] [Google Scholar]
  34. Mackworth-Young C. G. Cross-reactive idiotypes in sera from patients with leprosy, lupus and Lyme disease and from healthy individuals. Clin Exp Immunol. 1990 Jan;79(1):78–82. doi: 10.1111/j.1365-2249.1990.tb05130.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Mackworth-Young C., Sabbaga J., Schwartz R. S. Idiotypic markers of polyclonal B cell activation. Public idiotypes shared by monoclonal antibodies derived from patients with systemic lupus erythematosus or leprosy. J Clin Invest. 1987 Feb;79(2):572–581. doi: 10.1172/JCI112849. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Meng Q. H., Rauch J. Differences between human hybridoma platelet-binding antibodies derived from systemic lupus erythematosus patients and normal individuals. Autoimmunity. 1990;5(3):151–167. doi: 10.3109/08916939009002974. [DOI] [PubMed] [Google Scholar]
  37. Nakamura M., Burastero S. E., Ueki Y., Larrick J. W., Notkins A. L., Casali P. Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus. J Immunol. 1988 Dec 15;141(12):4165–4172. [PubMed] [Google Scholar]
  38. Naparstek Y., André-Schwartz J., Manser T., Wysocki L. J., Breitman L., Stollar B. D., Gefter M., Schwartz R. S. A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus. J Exp Med. 1986 Aug 1;164(2):614–626. doi: 10.1084/jem.164.2.614. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Naparstek Y., Duggan D., Schattner A., Madaio M. P., Goni F., Frangione B., Stollar B. D., Kabat E. A., Schwartz R. S. Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies. J Exp Med. 1985 Jun 1;161(6):1525–1538. doi: 10.1084/jem.161.6.1525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Persson M. A., Brown S. E., Steward M. W., Hammarström L., Smith C. I., Howard C. R., Wahl M., Rynnel-Dagö B., Lefranc G., Carbonara A. O. IgG subclass-associated affinity differences of specific antibodies in humans. J Immunol. 1988 Jun 1;140(11):3875–3879. [PubMed] [Google Scholar]
  41. Pisetsky D. S., Jelinek D. F., McAnally L. M., Reich C. F., Lipsky P. E. In vitro autoantibody production by normal adult and cord blood B cells. J Clin Invest. 1990 Mar;85(3):899–903. doi: 10.1172/JCI114517. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Plater-Zyberk C., Maini R. N., Lam K., Kennedy T. D., Janossy G. A rheumatoid arthritis B cell subset expresses a phenotype similar to that in chronic lymphocytic leukemia. Arthritis Rheum. 1985 Sep;28(9):971–976. doi: 10.1002/art.1780280903. [DOI] [PubMed] [Google Scholar]
  43. Rauch J., Meng Q. H., Tannenbaum H. Lupus anticoagulant and antiplatelet properties of human hybridoma autoantibodies. J Immunol. 1987 Oct 15;139(8):2598–2604. [PubMed] [Google Scholar]
  44. Rubin R. L., Carr R. I. Anti-DNA activity of IgG F(ab')2 from normal human serum. J Immunol. 1979 Apr;122(4):1604–1607. [PubMed] [Google Scholar]
  45. Rustum Y. M., Slocum H. K., Wang G., Bakshi D., Kelly E., Buscaglia D., Wrzosek C., Early A. P., Preisler H. Relationship between plasma Ara-C and intracellular Ara-CTP pools under conditions of continuous infusion and high-dose Ara-C treatment. Med Pediatr Oncol. 1982;10 (Suppl 1):33–43. doi: 10.1002/mpo.2950100706. [DOI] [PubMed] [Google Scholar]
  46. Sabbaga J., Pankewycz O. G., Lufft V., Schwartz R. S., Madaio M. P. Cross-reactivity distinguishes serum and nephritogenic anti-DNA antibodies in human lupus from their natural counterparts in normal serum. J Autoimmun. 1990 Apr;3(2):215–235. doi: 10.1016/0896-8411(90)90142-f. [DOI] [PubMed] [Google Scholar]
  47. Sanz I., Casali P., Thomas J. W., Notkins A. L., Capra J. D. Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families. J Immunol. 1989 Jun 1;142(11):4054–4061. [PubMed] [Google Scholar]
  48. Sanz I., Dang H., Takei M., Talal N., Capra J. D. VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes. J Immunol. 1989 Feb 1;142(3):883–887. [PubMed] [Google Scholar]
  49. Sela O., el-Roeiy A., Isenberg D. A., Kennedy R. C., Colaco C. B., Pinkhas J., Shoenfeld Y. A common anti-DNA idiotype in sera of patients with active pulmonary tuberculosis. Arthritis Rheum. 1987 Jan;30(1):50–56. doi: 10.1002/art.1780300107. [DOI] [PubMed] [Google Scholar]
  50. Seligmann M., Brouet J. C. Antibody activity of human myeloma globulins. Semin Hematol. 1973 Apr;10(2):163–177. [PubMed] [Google Scholar]
  51. Sestak A. L., Harley J. B., Yoshida S., Reichlin M. Lupus/Sjögren's autoantibody specificities in sera with paraproteins. J Clin Invest. 1987 Jul;80(1):138–144. doi: 10.1172/JCI113039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Shlomchik M. J., Marshak-Rothstein A., Wolfowicz C. B., Rothstein T. L., Weigert M. G. The role of clonal selection and somatic mutation in autoimmunity. 1987 Aug 27-Sep 2Nature. 328(6133):805–811. doi: 10.1038/328805a0. [DOI] [PubMed] [Google Scholar]
  53. Shlomchik M., Mascelli M., Shan H., Radic M. Z., Pisetsky D., Marshak-Rothstein A., Weigert M. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med. 1990 Jan 1;171(1):265–292. doi: 10.1084/jem.171.1.265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Shoenfeld Y., Ben-Yehuda O., Napartstek Y., Wilner Y., Frolichman R., Schattner A., Lavie G., Joshua H., Pinkhas J., Kennedy R. C. The detection of a common idiotype of anti-DNA antibodies in the sera of patients with monoclonal gammopathies. J Clin Immunol. 1986 May;6(3):194–204. doi: 10.1007/BF00918699. [DOI] [PubMed] [Google Scholar]
  55. Shoenfeld Y., Vilner Y., Coates A. R., Rauch J., Lavie G., Shaul D., Pinkhas J. Monoclonal anti-tuberculosis antibodies react with DNA, and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis. Clin Exp Immunol. 1986 Nov;66(2):255–261. [PMC free article] [PubMed] [Google Scholar]
  56. Shoenfeld Y., el-Roeiy A., Ben-Yehuda O., Pick A. I. Detection of anti-histone activity in sera of patients with monoclonal gammopathies. Clin Immunol Immunopathol. 1987 Feb;42(2):250–258. doi: 10.1016/0090-1229(87)90012-2. [DOI] [PubMed] [Google Scholar]
  57. Souroujon M., White-Scharf M. E., Andreschwartz J., Gefter M. L., Schwartz R. S. Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice. J Immunol. 1988 Jun 15;140(12):4173–4179. [PubMed] [Google Scholar]
  58. Suzuki N., Sakane T., Engleman E. G. Anti-DNA antibody production by CD5+ and CD5- B cells of patients with systemic lupus erythematosus. J Clin Invest. 1990 Jan;85(1):238–247. doi: 10.1172/JCI114418. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Thomas M. A., Frampton G., Isenberg D. A., Shoenfeld Y., Akinsola A., Ramzy M., Lilleywhite J., Williams D. G. A common anti-DNA antibody idiotype and anti-phospholipid antibodies in sera from patients with schistosomiasis and filariasis with and without nephritis. J Autoimmun. 1989 Dec;2(6):803–811. doi: 10.1016/0896-8411(89)90006-1. [DOI] [PubMed] [Google Scholar]
  60. Watts R. A., Ravirajan C. T., Staines N. A., Isenberg D. A. A human fetal monoclonal DNA-binding antibody shares idiotypes with fetal and adult murine monoclonal DNA-binding antibodies. Immunology. 1990 Mar;69(3):348–354. [PMC free article] [PubMed] [Google Scholar]
  61. Watts R. A., Williams W., Le Page S., Norden A., Soltys A., Swana G., Addison I., Hay F. C., Isenberg D. A. Analysis of autoantibody reactivity and common idiotype PR4 expression of myeloma proteins. J Autoimmun. 1989 Oct;2(5):689–700. doi: 10.1016/s0896-8411(89)80007-1. [DOI] [PubMed] [Google Scholar]
  62. Williams W., Zumla A., Behrens R., Locniskar M., Voller A., McAdam K. P., Isenberg D. A. Studies of a common idiotype PR4 in autoimmune rheumatic disease. Arthritis Rheum. 1988 Sep;31(9):1097–1104. doi: 10.1002/art.1780310903. [DOI] [PubMed] [Google Scholar]
  63. Youinou P., Mackenzie L., Jouquan J., Le Goff P., Lydyard P. M. CD5 positive B cells in patients with rheumatoid arthritis: phorbol ester mediated enhancement of detection. Ann Rheum Dis. 1987 Jan;46(1):17–22. doi: 10.1136/ard.46.1.17. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Youinou P., Mackenzie L., le Masson G., Papadopoulos N. M., Jouquan J., Pennec Y. L., Angelidis P., Katsikis P., Moutsopoulos H. M., Lydyard P. M. CD5-expressing B lymphocytes in the blood and salivary glands of patients with primary Sjögren's syndrome. J Autoimmun. 1988 Apr;1(2):185–194. doi: 10.1016/0896-8411(88)90025-x. [DOI] [PubMed] [Google Scholar]
  65. Zouali M., Fine J. M., Eyquem A. Anti-DNA autoantibody activity and idiotypic relationships of human monoclonal proteins. Eur J Immunol. 1984 Dec;14(12):1085–1089. doi: 10.1002/eji.1830141204. [DOI] [PubMed] [Google Scholar]
  66. el-Roiey A., Gross W. L., Luedemann J., Isenberg D. A., Shoenfeld Y. Preferential secretion of a common anti-DNA idiotype (16/6 Id) and anti-polynucleotide antibodies by normal mononuclear cells following stimulation with Klebsiella pneumoniae. Immunol Lett. 1986 Jun;12(5-6):313–319. doi: 10.1016/0165-2478(86)90036-2. [DOI] [PubMed] [Google Scholar]
  67. el-Roiey A., Sela O., Isenberg D. A., Feldman R., Colaco B. C., Kennedy R. C., Shoenfeld Y. The sera of patients with Klebsiella infections contain a common anti-DNA idiotype (16/6) Id and anti-polynucleotide activity. Clin Exp Immunol. 1987 Mar;67(3):507–515. [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES