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. 1991 Mar;50(3):184–186. doi: 10.1136/ard.50.3.184

Rhabdomyolysis after intramuscular iron-dextran in malabsorption.

W D Foulkes 1, C Sewry 1, J Calam 1, H J Hodgson 1
PMCID: PMC1004372  PMID: 2015014

Abstract

The case of a 59 year old white man who had chronic malabsorption and selective IgA deficiency with severe iron deficiency is reported. In addition, he was deficient in vitamin E and selenium, important antioxidants which protect against lipid peroxidation. He was intolerant of oral iron and when treated with iron-dextran developed symptoms suggestive of polymyositis with evidence of rhabdomyolysis. It is suggested that free iron within iron-dextran activated free radicals, initiating lipid peroxidation and leading to polymyositis, rhabdomyolysis, and myoglobulinuria.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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