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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1992 Jan;51(1):123–125. doi: 10.1136/ard.51.1.123

Selective IgA deficiency associated with glomerulonephritis and oligoarthritis.

J P Camilleri 1, R H Moore 1, D F Griffiths 1, B D Williams 1
PMCID: PMC1004635  PMID: 1540017

Abstract

A 59 year old woman with selective IgA deficiency associated with oligoarthritis and glomerulonephritis is described. She was seropositive for rheumatoid factor and renal histological examination showed a focal glomerulonephritis. High titre rheumatoid factor and a focal glomerulonephritis were also present in the only other well documented report of selective IgA deficiency and renal disease. Histological examination of the kidney suggested that the glomerulonephritis was mediated by immune complexes.

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Selected References

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  1. Ammann A. J., Hong R. Selective IgA deficiency: presentation of 30 cases and a review of the literature. Medicine (Baltimore) 1971 May;50(3):223–236. [PubMed] [Google Scholar]
  2. Batchelor J. R., Fielder A. H., Walport M. J., David J., Lord D. K., Davey N., Dodi I. A., Malasit P., Wanachiwanawin W., Bernstein R. Family study of the major histocompatibility complex in HLA DR3 negative patients with systemic lupus erythematosus. Clin Exp Immunol. 1987 Nov;70(2):364–371. [PMC free article] [PubMed] [Google Scholar]
  3. Cassidy J. T., Burt A., Petty R., Sullivan D. Selective IgA deficiency in connective tissue diseases. N Engl J Med. 1969 Jan 30;280(5):275–275. doi: 10.1056/nejm196901302800520. [DOI] [PubMed] [Google Scholar]
  4. Cuesta B., Fernández J., Pardo J., Páramo J. A., Gómez C., Rocha E. Evan's syndrome, chronic active hepatitis and focal glomerulonephritis in IgA deficiency. Acta Haematol. 1986;75(1):1–5. doi: 10.1159/000206070. [DOI] [PubMed] [Google Scholar]
  5. Cunningham-Rundles C., Pudifin D. J., Armstrong D., Good R. A. Selective IgA deficiency and neoplasia. Vox Sang. 1980 Feb;38(2):61–67. doi: 10.1111/j.1423-0410.1980.tb02332.x. [DOI] [PubMed] [Google Scholar]
  6. Huntley C. C., Thorpe D. P., Lyerly A. D., Kelsey W. M. Rheumatoid arthritis with IgA deficiency. Am J Dis Child. 1967 Apr;113(4):411–418. doi: 10.1001/archpedi.1967.02090190057002. [DOI] [PubMed] [Google Scholar]
  7. Koistinen J., Sarna S. Immunological abnormalities in the sera of IgA-deficient blood donors. Vox Sang. 1975;29(3):203–213. doi: 10.1111/j.1423-0410.1975.tb00495.x. [DOI] [PubMed] [Google Scholar]
  8. Koistinen J. Selective IgA deficiency in blood donors. Vox Sang. 1975;29(3):192–202. doi: 10.1111/j.1423-0410.1975.tb00494.x. [DOI] [PubMed] [Google Scholar]
  9. Morgan G., Levinsky R. J. Clinical significance of IgA deficiency. Arch Dis Child. 1988 Jun;63(6):579–581. doi: 10.1136/adc.63.6.579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Schaffer F. M., Palermos J., Zhu Z. B., Barger B. O., Cooper M. D., Volanakis J. E. Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes. Proc Natl Acad Sci U S A. 1989 Oct;86(20):8015–8019. doi: 10.1073/pnas.86.20.8015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Schifferli J. A., Ng Y. C., Peters D. K. The role of complement and its receptor in the elimination of immune complexes. N Engl J Med. 1986 Aug 21;315(8):488–495. doi: 10.1056/NEJM198608213150805. [DOI] [PubMed] [Google Scholar]
  12. WEST C. D., HONG R., HOLLAND N. H. Immunoglobulin levels from the newborn period to adulthood and in immunoglobulin deficiency states. J Clin Invest. 1962 Nov;41:2054–2064. doi: 10.1172/JCI104663. [DOI] [PMC free article] [PubMed] [Google Scholar]

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