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. 1992 Sep;51(9):1053–1055. doi: 10.1136/ard.51.9.1053

Correlation of antibodies to ribosomal P protein with psychosis in patients with systemic lupus erythematosus.

Y Nojima 1, S Minota 1, A Yamada 1, F Takaku 1, S Aotsuka 1, R Yokohari 1
PMCID: PMC1004836  PMID: 1417136

Abstract

Ninety one Japanese patients with systemic lupus erythematosus (SLE) were studied to determine the clinical significance of antibodies to ribosomal P protein (anti-P). Anti-P was detected by western blotting in 38 of 91 patients (42%). Clinical symptoms of SLE were compared between patients with and without anti-P. The occurrence of lupus psychosis was significantly higher in patients with anti-P than in those without anti-P (9/38 v 1/53). No significant association was found between anti-P and other symptoms of SLE. These data strongly support the suggestion proposed by previous workers that anti-P is a marker autoantibody for the development of lupus psychosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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