Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1992 Dec;51(12):1332–1334. doi: 10.1136/ard.51.12.1332

Long term prognosis in yersinia arthritis: clinical and serological findings.

J D Herrlinger 1, J U Asmussen 1
PMCID: PMC1004931  PMID: 1485817

Abstract

Twenty two patients were followed up for a mean of 10.7 years after acute yersinia arthritis. Their clinical course, agglutination antibodies, antibodies against plasmid coded yersinia proteins, and laboratory parameters of inflammation were analysed. The clinical findings were unremarkable. Serum agglutinating antibodies against Yersinia enterocolitica were not found in any patient. Ten patients had no antibodies against plasmid coded bacterial proteins. Five patients showed IgG antibodies, one patient had an IgA and IgG result of questionable significance, and six patients had IgA and IgG antibodies in the immunoblot reaction. No evidence of systemic inflammation was found. The persistence of IgA or IgG antibodies, or both, did not have a discernible influence on the clinical course. The development of erosive changes in the sacroiliac joints occurred independently of yersinia infection.

Full text

PDF
1332

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aho K., Ahvonen P., Lassus A., Sievers K., Tiilikainen A. HL-A 27 in reactive arthritis. A study of Yersinia arthritis and Reiter's disease. Arthritis Rheum. 1974 Sep-Oct;17(5):521–526. doi: 10.1002/art.1780170505. [DOI] [PubMed] [Google Scholar]
  2. Ahvonen P. Human yersiniosis in Finland. II. Clinical features. Ann Clin Res. 1972 Feb;4(1):39–48. [PubMed] [Google Scholar]
  3. Ahvonen P., Sievers K., Aho K. Arthritis associated with Yersinia enterocolitica infection. Acta Rheumatol Scand. 1969;15(3):232–253. doi: 10.3109/rhe1.1969.15.issue-1-4.32. [DOI] [PubMed] [Google Scholar]
  4. Chalmers A., Kaprove R. E., Reynolds W. J., Urowitz M. B. Postdiarrheal arthropathy of Yersinia pseudotuberculosis. Can Med Assoc J. 1978 Mar 4;118(5):515–516. [PMC free article] [PubMed] [Google Scholar]
  5. Heesemann J., Gaede K. Mechanisms involved in the pathogenesis of Yersinia infections. Rheumatol Int. 1989;9(3-5):213–217. doi: 10.1007/BF00271883. [DOI] [PubMed] [Google Scholar]
  6. Heesemann J., Gross U., Schmidt N., Laufs R. Immunochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. grown in calcium-deficient media. Infect Immun. 1986 Nov;54(2):561–567. doi: 10.1128/iai.54.2.561-567.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Herrlinger J. D., Wuthe H. H. Yersinia-arthritis. Med Klin. 1979 Nov 9;74(45):1681–1685. [PubMed] [Google Scholar]
  8. Lahesmaa-Rantala R., Granfors K., Isomäki H., Toivanen A. Yersinia specific immune complexes in the synovial fluid of patients with yersinia triggered reactive arthritis. Ann Rheum Dis. 1987 Jul;46(7):510–514. doi: 10.1136/ard.46.7.510. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Lahesmaa-Rantala R., Granfors K., Kekomäki R., Toivanen A. Circulating yersinia specific immune complexes after acute yersiniosis: a follow up study of patients with and without reactive arthritis. Ann Rheum Dis. 1987 Feb;46(2):121–126. doi: 10.1136/ard.46.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Leirisalo-Repo M., Suoranta H. Ten-year follow-up study of patients with Yersinia arthritis. Arthritis Rheum. 1988 Apr;31(4):533–537. doi: 10.1002/art.1780310410. [DOI] [PubMed] [Google Scholar]
  11. Merilahti-Palo R., Söderström K. O., Lahesmaa-Rantala R., Granfors K., Toivanen A. Bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis. Ann Rheum Dis. 1991 Feb;50(2):87–90. doi: 10.1136/ard.50.2.87. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Winblad S. Arthritis associated with Yersinia enterocolitica infections. Scand J Infect Dis. 1975;7(3):191–195. doi: 10.3109/inf.1975.7.issue-3.07. [DOI] [PubMed] [Google Scholar]
  13. de Koning J., Heesemann J., Hoogkamp-Korstanje J. A., Festen J. J., Houtman P. M., van Oijen P. L. Yersinia in intestinal biopsy specimens from patients with seronegative spondyloarthropathy: correlation with specific serum IgA antibodies. J Infect Dis. 1989 Jan;159(1):109–112. doi: 10.1093/infdis/159.1.109. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES