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. 1993 Feb;52(2):158–160. doi: 10.1136/ard.52.2.158

Systemic amyloidosis AL with temporal artery involvement revealing lymphoplasmacytic malignancy in a man presenting as polymyalgia rheumatica.

P Lafforgue 1, E Senbel 1, D Figarella-Branger 1, J Boucraut 1, N Horschowsky 1, J F Pellissier 1, P C Acquaviva 1
PMCID: PMC1004998  PMID: 8447697

Abstract

A 68 year old man presented with a clinical and biological picture that suggested polymyalgia rheumatica. Temporal artery biopsy disclosed no inflammatory change but massive light chain amyloid deposits in the media. Further exploration showed a malignant lymphoplasmacytic haemopathy with a triclonal gammopathy and a muscular, rectal, and probable cardiac amyloidosis. Cryoglobulinaemia and high concentrations of soluble interleukin 2 receptor (sIL-2R) were also found. This is the fifth case with confirmed involvement of the temporal artery. The especially high sIL-2R concentration was thought to reflect the tumour mass rather than lymphocyte activation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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