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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1993 Mar;52(3):223–228. doi: 10.1136/ard.52.3.223

Yersinia associated arthritis in SHR rats: effect of the microbial status of the host.

C Gripenberg-Lerche 1, P Toivanen 1
PMCID: PMC1005022  PMID: 8484677

Abstract

Following the intravenous injection of live Yersinia enterocolitica O:8, 50-69% of SHR rats developed arthritis; these rats were antibody free against all rat pathogens tested. In contrast, only 20-25% of SHR rats which had serum antibodies against Bacillus piliformis, Kilham rat virus, and Toolan H-1 virus developed arthritis. The results indicate that the microbial load of the host has a profound effect on the susceptibility to experimental arthritis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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