Skip to main content
PMC home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1994 Jan;53(1):3–5. doi: 10.1136/ard.53.1.3

Immunochemical markers of joint inflammation, skeletal damage and repair: where are we now?

A R Poole 1
PMCID: PMC1005233  PMID: 8311551

Full text

PDF
3

Images in this article

4Image
on p.4

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Caterson B., Mahmoodian F., Sorrell J. M., Hardingham T. E., Bayliss M. T., Carney S. L., Ratcliffe A., Muir H. Modulation of native chondroitin sulphate structure in tissue development and in disease. J Cell Sci. 1990 Nov;97(Pt 3):411–417. doi: 10.1242/jcs.97.3.411. [DOI] [PubMed] [Google Scholar]
  2. Dahlberg L., Ryd L., Heinegård D., Lohmander L. S. Proteoglycan fragments in joint fluid. Influence of arthrosis and inflammation. Acta Orthop Scand. 1992 Aug;63(4):417–423. doi: 10.3109/17453679209154758. [DOI] [PubMed] [Google Scholar]
  3. Engström-Laurent A., Hällgren R. Circulating hyaluronate in rheumatoid arthritis: relationship to inflammatory activity and the effect of corticosteroid therapy. Ann Rheum Dis. 1985 Feb;44(2):83–88. doi: 10.1136/ard.44.2.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Engström-Laurent A., Hällgren R. Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness. Arthritis Rheum. 1987 Dec;30(12):1333–1338. doi: 10.1002/art.1780301203. [DOI] [PubMed] [Google Scholar]
  5. Forslind K., Eberhardt K., Jonsson A., Saxne T. Increased serum concentrations of cartilage oligomeric matrix protein. A prognostic marker in early rheumatoid arthritis. Br J Rheumatol. 1992 Sep;31(9):593–598. doi: 10.1093/rheumatology/31.9.593. [DOI] [PubMed] [Google Scholar]
  6. Goldberg R. L., Huff J. P., Lenz M. E., Glickman P., Katz R., Thonar E. J. Elevated plasma levels of hyaluronate in patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum. 1991 Jul;34(7):799–807. doi: 10.1002/art.1780340704. [DOI] [PubMed] [Google Scholar]
  7. Hanson D. A., Weis M. A., Bollen A. M., Maslan S. L., Singer F. R., Eyre D. R. A specific immunoassay for monitoring human bone resorption: quantitation of type I collagen cross-linked N-telopeptides in urine. J Bone Miner Res. 1992 Nov;7(11):1251–1258. doi: 10.1002/jbmr.5650071119. [DOI] [PubMed] [Google Scholar]
  8. Heinegård D., Inerot S., Wieslander J., Lindblad G. A method for the quantification of cartilage proteoglycan structures liberated to the synovial fluid during developing degenerative joint disease. Scand J Clin Lab Invest. 1985 Sep;45(5):421–427. doi: 10.1080/00365518509155238. [DOI] [PubMed] [Google Scholar]
  9. Lohmander L. S., Dahlberg L., Ryd L., Heinegård D. Increased levels of proteoglycan fragments in knee joint fluid after injury. Arthritis Rheum. 1989 Nov;32(11):1434–1442. doi: 10.1002/anr.1780321113. [DOI] [PubMed] [Google Scholar]
  10. Lohmander L. S., Saxne T., Heinegård D. K. Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis. Ann Rheum Dis. 1994 Jan;53(1):8–13. doi: 10.1136/ard.53.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Manicourt D. H., Triki R., Fukuda K., Devogelaer J. P., Nagant de Deuxchaisnes C., Thonar E. J. Levels of circulating tumor necrosis factor alpha and interleukin-6 in patients with rheumatoid arthritis. Relationship to serum levels of hyaluronan and antigenic keratan sulfate. Arthritis Rheum. 1993 Apr;36(4):490–499. doi: 10.1002/art.1780360409. [DOI] [PubMed] [Google Scholar]
  12. Mehraban F., Finegan C. K., Moskowitz R. W. Serum keratan sulfate. Quantitative and qualitative comparisons in inflammatory versus noninflammatory arthritides. Arthritis Rheum. 1991 Apr;34(4):383–392. doi: 10.1002/art.1780340403. [DOI] [PubMed] [Google Scholar]
  13. Oldberg A., Antonsson P., Lindblom K., Heinegård D. COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. J Biol Chem. 1992 Nov 5;267(31):22346–22350. [PubMed] [Google Scholar]
  15. Paimela L., Heiskanen A., Kurki P., Helve T., Leirisalo-Repo M. Serum hyaluronate level as a predictor of radiologic progression in early rheumatoid arthritis. Arthritis Rheum. 1991 Jul;34(7):815–821. doi: 10.1002/art.1780340706. [DOI] [PubMed] [Google Scholar]
  16. Poole A. R., Witter J., Roberts N., Piccolo F., Brandt R., Paquin J., Baron M. Inflammation and cartilage metabolism in rheumatoid arthritis. Studies of the blood markers hyaluronic acid, orosomucoid, and keratan sulfate. Arthritis Rheum. 1990 Jun;33(6):790–799. doi: 10.1002/art.1780330605. [DOI] [PubMed] [Google Scholar]
  17. Ratcliffe A., Shurety W., Caterson B. The quantitation of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy. Arthritis Rheum. 1993 Apr;36(4):543–551. doi: 10.1002/art.1780360416. [DOI] [PubMed] [Google Scholar]
  18. Rizkalla G., Reiner A., Bogoch E., Poole A. R. Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease. J Clin Invest. 1992 Dec;90(6):2268–2277. doi: 10.1172/JCI116113. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Saxne T., Glennås A., Kvien T. K., Melby K., Heinegård D. Release of cartilage macromolecules into the synovial fluid in patients with acute and prolonged phases of reactive arthritis. Arthritis Rheum. 1993 Jan;36(1):20–25. doi: 10.1002/art.1780360105. [DOI] [PubMed] [Google Scholar]
  20. Saxne T., Heinegård D. Involvement of nonarticular cartilage, as demonstrated by release of a cartilage-specific protein, in rheumatoid arthritis. Arthritis Rheum. 1989 Sep;32(9):1080–1086. doi: 10.1002/anr.1780320905. [DOI] [PubMed] [Google Scholar]
  21. Seibel M. J., Duncan A., Robins S. P. Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases. J Rheumatol. 1989 Jul;16(7):964–970. [PubMed] [Google Scholar]
  22. Shinmei M., Ito K., Matsuyama S., Yoshihara Y., Matsuzawa K. Joint fluid carboxy-terminal type II procollagen peptide as a marker of cartilage collagen biosynthesis. Osteoarthritis Cartilage. 1993 Apr;1(2):121–128. doi: 10.1016/s1063-4584(05)80027-5. [DOI] [PubMed] [Google Scholar]
  23. Spector T. D., Woodward L., Hall G. M., Hammond A., Williams A., Butler M. G., James I. T., Hart D. J., Thompson P. W., Scott D. L. Keratan sulphate in rheumatoid arthritis, osteoarthritis, and inflammatory diseases. Ann Rheum Dis. 1992 Oct;51(10):1134–1137. doi: 10.1136/ard.51.10.1134. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Thonar E. J., Lenz M. E., Klintworth G. K., Caterson B., Pachman L. M., Glickman P., Katz R., Huff J., Kuettner K. E. Quantification of keratan sulfate in blood as a marker of cartilage catabolism. Arthritis Rheum. 1985 Dec;28(12):1367–1376. doi: 10.1002/art.1780281209. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES