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[Preprint]. 2023 Mar 25:2023.03.25.534219. [Version 1] doi: 10.1101/2023.03.25.534219

Fig. 6. The relationship between pBI143 and its bacterial hosts.

Fig. 6.

(A) The average coverage of pBI143 and the corresponding coverage of predicted host genomes (Bacteroides, Parabacteroides and Phocaeicola) in 4,516 metagenomes. (B) Competition experiments in gnotobiotic mice between B. fragilis with and without pBI143. The proportion of pBI143-carrying cells in 6 mice in the initial inoculum, at Day 8 and at Day 14 are shown. (C) Four examples of pBI143 assembled from metagenomes that carry additional cargo genes. Gray genes are the canonical repA and mobA genes of naive pBI143; lilac genes are additional cargo.