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. 1992 Feb;51(2):259–261. doi: 10.1136/ard.51.2.259

Diuretic induced gout: a multifactorial condition.

J T Scott 1, C S Higgens 1
PMCID: PMC1005670  PMID: 1550414

Abstract

Fifteen patients with clinical gout occurring after long term treatment with diuretics were studied retrospectively. In all 15 patients one or more additional factors were present which might have contributed to the hyperuricaemia and gout. The most common of these was the impairment of the glomerular filtration rate. Twenty five other patients receiving long term treatment with diuretics who did not have gout were also studied. The concentrations of uric acid, urea, and creatinine were, in general, markedly lower in these patients than in those who had developed gout. It is concluded that diuretic induced gout occurs in patients in whom there is an additional cause of hyperuricaemia, usually impaired renal function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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