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. 2023 Mar 14;28(6):2622. doi: 10.3390/molecules28062622

Figure 1.

Figure 1

Metabolic pathways and known receptors of classical EICs. Abbreviations: 20-HETE—20-hydroxyeicosatetraenoic acid; BLT—leukotriene B4 receptor; COX—cyclooxygenase; CYP450—cytochrome P450; DP—prostaglandin D receptor; EET—epoxyeicosatrienoic acid; EP—prostaglandin E receptor; FP—prostaglandin F receptor; HpETE—hydroperoxyeicosatetraenoic acid; IP—prostacyclin I receptor; LOX—lipoxygenase; LT—leukotriene; LX—lipoxin; PG—prostaglandin; PGDS—prostaglandin D2 synthase; PGES—prostaglandin E synthase; PGFS—prostaglandin F synthase; PGI2—prostacyclin 2; PGIS—prostacyclin I synthase; PLA2—phospholipase A2; TP—thromboxane receptor; TXAS—thromboxane synthase.