Alexander S Powers
Alexander S Powers
1Department of Chemistry, Stanford University, Stanford, CA USA
2Department of Computer Science, Stanford University, Stanford, CA USA
3Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA USA
4Department of Structural Biology, Stanford University School of Medicine, Stanford, CA USA
5Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA USA
1,2,3,4,5,
Vi Pham
Vi Pham
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,
Wessel A C Burger
Wessel A C Burger
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
7ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,7,
Geoff Thompson
Geoff Thompson
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,
Yianni Laloudakis
Yianni Laloudakis
2Department of Computer Science, Stanford University, Stanford, CA USA
2,
Nicholas W Barnes
Nicholas W Barnes
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,
Patrick M Sexton
Patrick M Sexton
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
7ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,7,
Steven M Paul
Steven M Paul
8Karuna Therapeutics, Boston, MA USA
8,
Arthur Christopoulos
Arthur Christopoulos
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
7ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
9Neuromedicines Discovery Center, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,7,9,
David M Thal
David M Thal
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
7ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,7,
Christian C Felder
Christian C Felder
8Karuna Therapeutics, Boston, MA USA
8,
Celine Valant
Celine Valant
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
6,✉,
Ron O Dror
Ron O Dror
2Department of Computer Science, Stanford University, Stanford, CA USA
3Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA USA
4Department of Structural Biology, Stanford University School of Medicine, Stanford, CA USA
5Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA USA
2,3,4,5,✉
1Department of Chemistry, Stanford University, Stanford, CA USA
2Department of Computer Science, Stanford University, Stanford, CA USA
3Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA USA
4Department of Structural Biology, Stanford University School of Medicine, Stanford, CA USA
5Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA USA
6Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
7ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
8Karuna Therapeutics, Boston, MA USA
9Neuromedicines Discovery Center, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria Australia
Subject terms: G protein-coupled receptors, Cell signalling, Pharmacology, Computational chemistry
© The Author(s) 2023
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.