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. Author manuscript; available in PMC: 2023 Mar 30.
Published in final edited form as: Nature. 2022 Oct 26;611(7935):387–398. doi: 10.1038/s41586-022-05365-x

Extended Data Fig. 3. TAD boundary alteration and transcription.

Extended Data Fig. 3.

a, Illustration for how alteration of TAD boundary is defined in this study. b, COSMIC cancer-related genes that are located in TADs with recurrent change of boundary. Y axis is the number of incidences across different samples. c, Differential expression analysis of genes located inside recurrently altered TADs. P value by two-sided Student t-test.