Abstract
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive diseases. The patients with raised immunoreactive gastrin appear to form a separate population but the factors determining this separation remain obscure. Anti-inflammatory drugs, at least during short-term administration have no influence on immunoreactive gastrin concentrations.
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- Chapman C., Hutton W. N., Hayter C. J. The interference of human IgG with the double-antibody radioimmunoassay of thyrotrophic hormone and its clinical significance. Clin Sci Mol Med. 1974 May;46(5):651–654. doi: 10.1042/cs0460651. [DOI] [PubMed] [Google Scholar]
- HUNTER W. M., GREENWOOD F. C. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature. 1962 May 5;194:495–496. doi: 10.1038/194495a0. [DOI] [PubMed] [Google Scholar]
- KUNKEL H. G., MULLER-EBERHARD H. J., FUDENBERG H. H., TOMASI T. B. Gamma globulin complexes in rheumatoid arthritis and certain other conditions. J Clin Invest. 1961 Jan;40:117–129. doi: 10.1172/JCI104224. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Karim S. M., Carter D. C., Bhana D., Ganesan P. A. Effect of orally administered prostaglandin E 2 and its 15-methyl analogues on gastric secretion. Br Med J. 1973 Jan 20;1(5846):143–146. doi: 10.1136/bmj.1.5846.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lee P., Sturrock R. D., Kennedy A., Dick W. C. The evaluation of antirheumatic drugs. Curr Med Res Opin. 1973;1(7):427–443. doi: 10.1185/03007997309111705. [DOI] [PubMed] [Google Scholar]
- Rooney P. J., Dick W. C., Imrie R. C., Buchanan K. D. Animal model to study the relationship between immunoreactive gastrin and inflammatory arthritis. Nature. 1973 Dec 21;246(5434):497–498. doi: 10.1038/246497a0. [DOI] [PubMed] [Google Scholar]
- Rooney P. J., Dow T. G., Brooks P. M., Dick W. C., Buchanan K. D. Immunoreactive gastrin and gestation. Am J Obstet Gynecol. 1975 Aug 1;122(7):834–836. doi: 10.1016/0002-9378(75)90724-3. [DOI] [PubMed] [Google Scholar]
- Rooney P. J., Oakley C., Sturrock R. D., Dick W. C., Hayes J. R., Buchanan K. D. Effect of carbenoxolone upon immunoreactive secretin in patients with rheumatoid arthritis. Lancet. 1974 Apr 6;1(7858):592–593. doi: 10.1016/s0140-6736(74)92651-8. [DOI] [PubMed] [Google Scholar]
- Tapanes F. J., Rawson A. J., Hollander J. L. Serum anti-immunoglobulins in psoriatic arthritis as compared with rheumatoid arthritis. Arthritis Rheum. 1972 Mar-Apr;15(2):153–156. doi: 10.1002/art.1780150204. [DOI] [PubMed] [Google Scholar]
- Torrigiani G., Roitt I. M. Antiglobulin factors in sera from patients with rheumatoid arthritis and normal subjects. Quantitative estimation in different immunoglobulin classes. Ann Rheum Dis. 1967 Jul;26(4):334–340. doi: 10.1136/ard.26.4.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walsh J. H., Debas H. T., Grossman M. I. Pure human big gastrin. Immunochemical properties, disappearance half time, and acid-stimulating action in dogs. J Clin Invest. 1974 Aug;54(2):477–485. doi: 10.1172/JCI107783. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whaley K., Williamson J., Chisholm D. M., Webb J., Mason D. K., Buchanan W. W. Sjogren's syndrome. I. Sicca components. Q J Med. 1973 Apr;42(166):279–304. [PubMed] [Google Scholar]
- Yalow R. S., Berson S. A. And now, "big, big" gastrin. Biochem Biophys Res Commun. 1972 Jul 25;48(2):391–395. doi: 10.1016/s0006-291x(72)80063-9. [DOI] [PubMed] [Google Scholar]