Abstract
The technetium index was measured in 22 patients with rheumatoid arthritis, before and after 6 months' treatment either with penicillamine or with anti-inflammatory drugs. The index was calculated by dividing the sum of the count rates over both knees and both wrists by the dose of technetium given. In the penicillamine group there was a significant reduction in the technetium index and the changes correlated well with some clinical measurements of improvement. It is suggested that the technetium index is a useful objective measure of the effects of drugs with a specific activity in rheumatoid arthritis.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Berry H., Huskisson E. C. Isotopic indices as a measure of inflammation in rheumatoid arthritis. Ann Rheum Dis. 1974 Nov;33(6):523–525. doi: 10.1136/ard.33.6.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Boardman P. L., Hart F. D. Clinical measurement of the anti-inflammatory effects of salicylates in rheumatoid arthritis. Br Med J. 1967 Nov 4;4(5574):264–268. doi: 10.1136/bmj.4.5574.264. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oka M., Rekonen A., Ruotsi A. Tc-99m in the study of systemic inflammatory activity in rheumatoid arthritis. A preliminary report. Acta Rheumatol Scand. 1971;17(1):27–30. doi: 10.3109/rhe1.1971.17.issue-1-4.04. [DOI] [PubMed] [Google Scholar]
- Ritchie D. M., Boyle J. A., McInnes J. M., Jasani M. K., Dalakos T. G., Grieveson P., Buchanan W. W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med. 1968 Jul;37(147):393–406. [PubMed] [Google Scholar]