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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1977 Aug;36(4):378–380. doi: 10.1136/ard.36.4.378

Effect of D(-)penicillamine on chronic experimental arthritis in rabbits.

I M Hunneyball, G A Stewart, D R Stanworth
PMCID: PMC1006702  PMID: 901037

Abstract

Preliminary observations on the effect of D(-)penicillamine on chronic antigen-induced experimental arthritis in rabbits are reported. Daily oral administration of penicillamine, at a dose equivalent to that usually administered to rheumatoid arthritis patients, diminished the arthritis in 2 out of 3 animals as assessed by both measurement of joint circumference and histological examination.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Consden R., Doble A., Glynn L. E., Nind A. P. Production of a chronic arthritis with ovalbumin. Its retention in the rabbit knee joint. Ann Rheum Dis. 1971 May;30(3):307–315. doi: 10.1136/ard.30.3.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DUMONDE D. C., GLYNN L. E. The production of arthritis in rabbits by an immunological reaction to fibrin. Br J Exp Pathol. 1962 Aug;43:373–383. [PMC free article] [PubMed] [Google Scholar]
  3. Goldberg V. M., Lance E. M., Davis P. Experimental immune synovitis in the rabbit. Relative roles of cell mediated and humoral immunity. Arthritis Rheum. 1974 Nov-Dec;17(6):993–1005. doi: 10.1002/art.1780170612. [DOI] [PubMed] [Google Scholar]
  4. Liyanage S. P., Currey H. L. Failure of oral D-penicillamine to modify adjuvant arthritis or immune response in the rat. Ann Rheum Dis. 1972 Nov;31(6):521–521. doi: 10.1136/ard.31.6.521. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Schumacher K., Maerker-Alzer G., Preuss R. Effect of D-penicillamine on lymphocyte function. Arzneimittelforschung. 1975 Apr;25(4):603–606. [PubMed] [Google Scholar]

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