Fig. 5.

Distance traveled by young, middle-aged, and senile albino Swiss mice, submitted to impoverished and enriched environments.

Note. (A–B) Total distance traveled (m): (A) in the Elevated Plus Maze and (B) in the Open Field test. (C) Distance traveled (m) in the closed arm of the Elevated Plus Maze and (D) distance traveled (m) in the peripheral zone of the Open Field test. Values are expressed as mean ± standard error, highlighting the significant differences (p < 0.05): (#) significant differences between environments; (*) significant differences to 6 months and (+) about 12 months. Significance values were obtained through Analysis of Variance (ANOVA) 2 criteria (age and environment) and post Tukey test. IE – impoverished environment; EE – enriched environment.