Skip to main content
NCBI home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1976 Aug;35(4):381–384. doi: 10.1136/ard.35.4.381

Improvement in lacrimal and salivary secretions after alkali therapy in Sjøgren's syndrome with renal tubular acidosis.

C T Flynn, T W Negus, J McHardy, D J Rainford
PMCID: PMC1007401  PMID: 970999

Abstract

A patient with Sjøgren's syndrome developed renal tubular acidosis which led to systemic acidosis and potassium depletion. Treatment with Shohl's solution and potassium supplements was followed by subjective improvement in tear flow, salivary flow, and by disappearance of bronchitic symptoms. Detailed objective assessments were then made during the next year, twice on treatment and twice without. These confirmed the subjective impression of improvement.

Full text

PDF
381

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson L. G., Cummings N. A., Asofsky R., Hylton M. B., Tarpley T. M., Jr, Tomasi T. B., Jr, Wolf R. O., Schall G. L., Talal N. Salivary gland immunoglobulin and rheumatoid factor synthesis in Sjögren's syndrome. Natural history and response to treatment. Am J Med. 1972 Oct;53(4):456–463. doi: 10.1016/0002-9343(72)90141-6. [DOI] [PubMed] [Google Scholar]
  2. BLOCH K. J., BUCHANAN W. W., WOHL M. J., BUNIM J. J. SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES. Medicine (Baltimore) 1965 May;44:187–231. [PubMed] [Google Scholar]
  3. BLOCH K. J., BUNIM J. J. SJOEGREN'S SYNDROME AND ITS RELATION TO CONNECTIVE TISSUE DISEASES. J Chronic Dis. 1963 Aug;16:915–927. doi: 10.1016/0021-9681(63)90140-1. [DOI] [PubMed] [Google Scholar]
  4. COHEN A., WAY B. J. The association of renal tubular acidosis with hyperglobulinaemic purpura. Australas Ann Med. 1962 Aug;11:189–194. doi: 10.1111/imj.1962.11.3.189. [DOI] [PubMed] [Google Scholar]
  5. Chisholm D. M., Mason D. K. Salivary gland function in Sjögren's syndrome: a review. Br Dent J. 1973 Nov 6;135(9):393–399. doi: 10.1038/sj.bdj.4803096. [DOI] [PubMed] [Google Scholar]
  6. HUTH E. J., MAYOCK R. L., KERR R. M. Hyperthyroidism associated with renal tubular acidosis; discussion of possible relationship. Am J Med. 1959 May;26(5):818–826. doi: 10.1016/0002-9343(59)90240-2. [DOI] [PubMed] [Google Scholar]
  7. Hughes G. R., Whaley K. Sjögren's syndrome. Br Med J. 1972 Dec 2;4(5839):533–536. doi: 10.1136/bmj.4.5839.533. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Mason D. K., Harden R. M., Boyle J. A., Jasani M. K., Williamson J., Buchanan W. W. Salivary flow rates and iodide trapping capacity in patients with Sjögren's syndrome. Ann Rheum Dis. 1967 Jul;26(4):311–315. doi: 10.1136/ard.26.4.311. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Massry S. G., Preuss H. G., Maher J. F., Schreiner G. E. Renal tubular acidosis after cadaver kidney homotransplantation. Studies on mechanism. Am J Med. 1967 Feb;42(2):284–292. doi: 10.1016/0002-9343(67)90026-5. [DOI] [PubMed] [Google Scholar]
  10. Morris R. C., Jr, Fudenberg H. H. Impaired renal acidification in patients with hypergammaglobulinemia. Medicine (Baltimore) 1967 Jan;46(1):57–69. doi: 10.1097/00005792-196701000-00003. [DOI] [PubMed] [Google Scholar]
  11. SHEARN M. A., TU W. H. NEPHROGENIC DIABETIC INSIPIDUS AND OTHER DEFECTS OF RENAL TUBULAR FUNCTION IN SJOERGREN'S SYNDROME. Am J Med. 1965 Aug;39:312–318. doi: 10.1016/0002-9343(65)90057-4. [DOI] [PubMed] [Google Scholar]
  12. TALAL N., BUNIM J. J. THE DEVELOPMENT OF MALIGNANT LYMPHOMA IN THE COURSE OF SJOEGREN'S SYNDROME. Am J Med. 1964 Apr;36:529–540. doi: 10.1016/0002-9343(64)90101-9. [DOI] [PubMed] [Google Scholar]
  13. Talal N. Sjögren's syndrome. Bull Rheum Dis. 1966 Mar;16(7):404–407. [PubMed] [Google Scholar]
  14. WRONG O., DAVIES H. E. The excretion of acid in renal disease. Q J Med. 1959 Apr;28(110):259–313. [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES