Skip to main content
British Journal of Industrial Medicine logoLink to British Journal of Industrial Medicine
. 1985 May;42(5):291–300. doi: 10.1136/oem.42.5.291

Neurobehavioural effects of repeated occupational exposure to toluene and paint solvents.

N Cherry, H Hutchins, T Pace, H A Waldron
PMCID: PMC1007475  PMID: 3872680

Abstract

In studies of two workforces 44 men exposed to paint solvents and 52 men working with toluene were compared with age matched comparison groups of non-exposed workers. Scores on a series of performance tests were examined, the solvent exposed in each study functioning less well than their comparison group. The apparent deficit among the paint exposed workers was substantial, but this was reduced after allowance for estimated intellectual capacity. No deficit was apparent on rematching with a second comparison group of more appropriate measured capacity. No evidence was found of impaired nerve conduction in the ulnar or median nerves, and few clinical signs of neurological damage were apparent. Nevertheless, in an associated inquiry of neuropsychological symptoms among 236 painters and 128 non-exposed workers a highly significant excess of symptoms was found among those exposed to paint solvents.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Antti-Poika M. Prognosis of symptoms in patients with diagnosed chronic organic solvent intoxication. Int Arch Occup Environ Health. 1982;51(1):81–89. doi: 10.1007/BF00378413. [DOI] [PubMed] [Google Scholar]
  2. Arlien-Søborg P., Bruhn P., Gyldensted C., Melgaard B. Chronic painters' syndrome. Chronic toxic encephalopathy in house painters. Acta Neurol Scand. 1979 Sep;60(3):149–156. [PubMed] [Google Scholar]
  3. Axelson O., Hane M., Hogstedt C. A case-referent study on neuropsychiatric disorders among workers exposed to solvents. Scand J Work Environ Health. 1976 Mar;2(1):14–20. doi: 10.5271/sjweh.2826. [DOI] [PubMed] [Google Scholar]
  4. Bruhn P., Arlien-Søborg P., Gyldensted C., Christensen E. L. Prognosis in chronic toxic encephalopathy. A two-year follow-up study in 26 house painters with occupational encephalopathy. Acta Neurol Scand. 1981 Oct;64(4):259–272. [PubMed] [Google Scholar]
  5. Cherry N., Venables H., Waldron H. A., Wells G. G. Some observations on workers exposed to methylene chloride. Br J Ind Med. 1981 Nov;38(4):351–355. doi: 10.1136/oem.38.4.351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Elofsson S. A., Gamberale F., Hindmarsh T., Iregren A., Isaksson A., Johnsson I., Knave B., Lydahl E., Mindus P., Persson H. E. Exposure to organic solvents. A cross-sectional epidemiologic investigation on occupationally exposed care and industrial spray painters with special reference to the nervous system. Scand J Work Environ Health. 1980 Dec;6(4):239–273. doi: 10.5271/sjweh.2609. [DOI] [PubMed] [Google Scholar]
  7. Goldstein G., Welch R. B., Rennick P. M., Shelly C. H. The validity of a visual searching task as an indicator of brain damage. J Consult Clin Psychol. 1973 Dec;41(3):434–437. doi: 10.1037/h0035350. [DOI] [PubMed] [Google Scholar]
  8. Hane M., Axelson O., Blume J., Hogstedt C., Sundell L., Ydreborg B. Psychological function changes among house painters. Scand J Work Environ Health. 1977 Jun;3(2):91–99. doi: 10.5271/sjweh.2785. [DOI] [PubMed] [Google Scholar]
  9. Hänninen H., Eskelinen L., Husman K., Nurminen M. Behavioral effects of long-term exposure to a mixture of organic solvents. Scand J Work Environ Health. 1976 Dec;2(4):240–255. doi: 10.5271/sjweh.2805. [DOI] [PubMed] [Google Scholar]
  10. Juntunen J., Hernberg S., Eistola P., Hupli V. Exposure to industrial solvents and brain atrophy. A retrospective study of pneumoencephalographic findings among 37 patients with exposure to industrial solvents. Eur Neurol. 1980;19(6):366–375. doi: 10.1159/000115176. [DOI] [PubMed] [Google Scholar]
  11. Juntunen J., Hupli V., Hernberg S., Luisto M. Neurological picture of organic solvent poisoning in industry. A retrospective clinical study of 37 patients. Int Arch Occup Environ Health. 1980;46(3):219–231. doi: 10.1007/BF00380012. [DOI] [PubMed] [Google Scholar]
  12. Olsen J., Sabroe S. A case-reference study of neuropsychiatric disorders among workers exposed to solvents in the Danish wood and furniture industry. Scand J Soc Med Suppl. 1980;16:44–49. [PubMed] [Google Scholar]
  13. Wilkinson R. T., Houghton D. Field test of arousal: a portable reaction timer with data storage. Hum Factors. 1982 Aug;24(4):487–493. doi: 10.1177/001872088202400409. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Industrial Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES