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. 1985 Dec;42(12):815–823. doi: 10.1136/oem.42.12.815

Is the Armadale epidemic over? Air pollution and mortality from lung cancer and other diseases, 1961-82.

O L Lloyd, F L Williams, F A Gailey
PMCID: PMC1007585  PMID: 4074653

Abstract

In Armadale, a town in central Scotland, the standardised mortality ratios (SMRs) for lung cancer were exceptionally high during 1968-74. A large cluster of cases was found in a residential zone downwind from a foundry. In the present study death certificates in the mortality registers of three town parishes were analysed for 1961-82 and the time trends of mortality from major categories of disease were examined. The distribution of mortality from lung cancer within Armadale's six residential zones was compared with that of the other diseases for the periods 1968-75 and 1976-82; the zone of particular interest was that containing the original cluster of lung cancer. The distribution of lung cancer was also compared with the pattern of air pollution by metals, collected by Sphagnum moss bags. The annual numbers of deaths from respiratory cancer in Armadale rose to a plateau in 1968-77; after a fall during 1978-80, the numbers returned in 1981 and 1982 to their previous high values. Between 1968-75 and 1976-82 the mean SMRs for all the disease categories except respiratory cancer rose. The SMR for total mortality in 1976-82 was the same as in preceding years when the standardised death rate for Armadale was the highest for Scotland in the annual reports of the Registrar General. In the zone with the highest mortality from lung cancer in 1968-75 the SMR for that disease continued to be higher than expected. That zone also showed the highest SMRs for cancer of the upper alimentary tract, cerebrovascular disease, hypertension, and coronary heart disease; its SMR for bronchitis was the second highest in the town. Pollution studies indicated that zones with high SMRs for respiratory and non-respiratory cancer were exposed to air pollution by metals. The temporal and spatial patterns are consistent with the view that the problem of mortality from cancer and non-malignant diseases in Armadale remains.

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Selected References

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  1. Alderson M. R., Bayliss R. I., Clarke C. A., Whitfield A. G. Death certification. Br Med J (Clin Res Ed) 1983 Aug 13;287(6390):444–445. doi: 10.1136/bmj.287.6390.444. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brinkley D., Haybittle J. L., Alderson M. R. Death certification in cancer of the breast. Br Med J (Clin Res Ed) 1984 Aug 25;289(6443):465–467. doi: 10.1136/bmj.289.6443.465. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Busuttil A., Kemp I. W., Heasman M. A. The accuracy of medical certificates of cause of death. Health Bull (Edinb) 1981 May;39(3):146–152. [PubMed] [Google Scholar]
  4. Gailey F. A., Lloyd O. L. A wind-tunnel study of the flow of air pollution in Armadale, central Scotland. Ecol Dis. 1983;2(4):419–431. [PubMed] [Google Scholar]
  5. Gardner M. J. Mapping cancer mortality in England and Wales. Br Med Bull. 1984 Oct;40(4):320–328. doi: 10.1093/oxfordjournals.bmb.a071998. [DOI] [PubMed] [Google Scholar]
  6. Jacobson B. S. The role of air pollution and other factors in local variations in general mortality and cancer mortality. Arch Environ Health. 1984 Jul-Aug;39(4):306–313. doi: 10.1080/00039896.1984.10545855. [DOI] [PubMed] [Google Scholar]
  7. Lawther P. J., Waller R. E., Henderson M. Air pollution and exacerbations of bronchitis. Thorax. 1970 Sep;25(5):525–539. doi: 10.1136/thx.25.5.525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Levine R. S., Witte J. Geographical correlations of colon and breast cancer. Lancet. 1984 Jul 28;2(8396):222–222. doi: 10.1016/s0140-6736(84)90502-6. [DOI] [PubMed] [Google Scholar]
  9. Lloyd O. L., Barclay R. Hypothesis. A short latent period for respiratory cancer in a 'susceptible' population. Community Med. 1979 Aug;1(3):210–220. [PubMed] [Google Scholar]
  10. Lloyd O. L., MacDonald J. Continuous epidemiological mapping--a needed public health watchdog. Public Health. 1984 Nov;98(6):321–326. doi: 10.1016/s0033-3506(84)80024-4. [DOI] [PubMed] [Google Scholar]
  11. Lloyd O. L. Respiratory-cancer clustering associated with localised industrial air pollution. Lancet. 1978 Feb 11;1(8059):318–320. doi: 10.1016/s0140-6736(78)90084-3. [DOI] [PubMed] [Google Scholar]
  12. Lloyd O. L., Smith G., Lloyd M. M., Holland Y., Gailey F. Raised mortality from lung cancer and high sex ratios of births associated with industrial pollution. Br J Ind Med. 1985 Jul;42(7):475–480. doi: 10.1136/oem.42.7.475. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. MARTIN A. E. MORTALITY AND MORBIDITY STATISTICS AND AIR POLLUTION. Proc R Soc Med. 1964 Oct;57:SUPPL–SUPPL:975. doi: 10.1177/003591576405710P202. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Medical aspects of death certification. A joint report of the Royal College of Physicians and the Royal College of Pathologists. J R Coll Physicians Lond. 1982 Oct;16(4):206–218. [PubMed] [Google Scholar]
  15. Percy C., Stanek E., 3rd, Gloeckler L. Accuracy of cancer death certificates and its effect on cancer mortality statistics. Am J Public Health. 1981 Mar;71(3):242–250. doi: 10.2105/ajph.71.3.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Wynder E. L., Hyams L., Shigematsu T. Correlations of international cancer death rates. An epidemiological exercise. Cancer. 1967 Jan;20(1):113–126. doi: 10.1002/1097-0142(1967)20:1<113::aid-cncr2820200117>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]

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