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. 1986 May;43(5):327–331. doi: 10.1136/oem.43.5.327

Branchial challenge of normal subjects with the endotoxin of Enterobacter agglomerans isolated from cotton dust.

J P Jamison, R C Lowry
PMCID: PMC1007656  PMID: 3707870

Abstract

Endotoxin produced by a culture of Enterobacter agglomerans isolated from cotton dust was inhaled by 12 normal subjects. No significant airway constriction was obtained in doses equivalent to those experienced in a workshift in a dusty mill. There was a statistically significant difference between this result and the bronchoconstriction that had occurred after flax dust inhalation in the same subjects. It is suggested that Enterobacter agglomerans endotoxin is not the causative agent of the acute bronchoconstriction that follows inhalation of textile dust.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANTWEILER H. Histamine liberation by cotton dust extracts: evidence against its causation by bacterial endotoxins. Br J Ind Med. 1961 Apr;18:130–132. doi: 10.1136/oem.18.2.130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Buck M. G., Bouhuys A. Byssinosis: airway constrictor response to cotton bracts. Lung. 1980;158(1):25–32. doi: 10.1007/BF02713699. [DOI] [PubMed] [Google Scholar]
  3. Cavagna G., Foà V., Vigliani E. C. Effects in man and rabbits of inhalation of cotton dust or extracts and purified endotoxins. Br J Ind Med. 1969 Oct;26(4):314–321. doi: 10.1136/oem.26.4.314. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cinkotai F. F., Lockwood M. G., Rylander R. Airborne micro-organisms and prevalence of byssinotic symptoms in cotton mills. Am Ind Hyg Assoc J. 1977 Oct;38(10):554–559. doi: 10.1080/0002889778507669. [DOI] [PubMed] [Google Scholar]
  5. Etzel K. R., Swerdel M. R., Swerdel J. N., Cousins R. J. Endotoxin-induced changes in copper and zinc metabolism in the Syrian hamster. J Nutr. 1982 Dec;112(12):2363–2373. doi: 10.1093/jn/112.12.2363. [DOI] [PubMed] [Google Scholar]
  6. Helander I., Salkinoja-Salonen M., Rylander R. Chemical structure and inhalation toxicity of lipopolysaccharides from bacteria on cotton. Infect Immun. 1980 Sep;29(3):859–862. doi: 10.1128/iai.29.3.859-862.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Jamison J. P., Langlands J. H., Bodel C. C. Ventilatory responses of normal subjects to flax dust inhalation: the protective effect of autoclaving the flax. Br J Ind Med. 1985 Mar;42(3):196–201. doi: 10.1136/oem.42.3.196. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lopez Merino V., Llopis Lombart R., Flores Marco R., Barbero Carnicero A., Gomez Guillen F., Bouhuys A. Arterial blood gas tensions and lung function during acute responses to hemp dust. Am Rev Respir Dis. 1973 May;107(5):809–815. doi: 10.1164/arrd.1973.107.5.809. [DOI] [PubMed] [Google Scholar]
  9. Lüderitz O., Galanos C., Lehmann V., Mayer H., Rietschel E. T., Weckesser J. Chemical structure and biological activities of lipid A's from various bacterial families. Naturwissenschaften. 1978 Nov;65(11):578–585. doi: 10.1007/BF00364907. [DOI] [PubMed] [Google Scholar]
  10. Merchant J. A., Halprin G. M., Hudson A. R., Kilburn K. H., McKenzie W. M., Jr, Bermanzohn P., Hurst D. J., Hamilton J. D., Germino V. H., Jr Evaluation before and after exposure--the pattern of physiological response to cotton dust. Ann N Y Acad Sci. 1974;221:38–43. doi: 10.1111/j.1749-6632.1974.tb28196.x. [DOI] [PubMed] [Google Scholar]
  11. Muittari A., Rylander R., Salkinoja-Salonen M. Endotoxin and bath-water fever. Lancet. 1980 Jul 12;2(8185):89–89. doi: 10.1016/s0140-6736(80)92965-7. [DOI] [PubMed] [Google Scholar]
  12. PERNIS B., VIGLIANI E. C., CAVAGNA C., FINULLI M. The role of bacterial endotoxins in occupational diseases caused by inhaling vegetable dusts. Br J Ind Med. 1961 Apr;18:120–129. doi: 10.1136/oem.18.2.120. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Rylander R., Lundholm M. Bacterial contamination of cotton and cotton dust and effects on the lung. Br J Ind Med. 1978 Aug;35(3):204–207. doi: 10.1136/oem.35.3.204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Rylander R., Nordstrand A., Snella M. C. Bacterial contamination of organic dusts: effects on pulmonary cell reactions. Arch Environ Health. 1975 Mar;30(3):137–140. doi: 10.1080/00039896.1975.10666662. [DOI] [PubMed] [Google Scholar]
  15. TUFFNELL P. Experimental byssinosis. Br J Ind Med. 1960 Oct;17:307–309. doi: 10.1136/oem.17.4.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. TUFFNELL P. The relationship of byssinosis to the bacteria and fungi in the air of textile mills. Br J Ind Med. 1960 Oct;17:304–306. doi: 10.1136/oem.17.4.304. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Van der Zwan J. C., Orie N. G., Kauffman H. F., Wiers P. W., de Vries K. Bronchial obstructive reactions after inhalation with endotoxin and precipitinogens of Haemophilus influenzae in patients with chronic non-specific lung disease. Clin Allergy. 1982 Nov;12(6):547–559. doi: 10.1111/j.1365-2222.1982.tb02553.x. [DOI] [PubMed] [Google Scholar]
  18. Wildfeuer A., Heymer B., Schleifer K. H., Haferkamp O. Investigations on the specificity of the Limulus test for the detection of endotoxin. Appl Microbiol. 1974 Nov;28(5):867–871. doi: 10.1128/am.28.5.867-871.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Zuskin E., Valic F., Bouhuys A. Byssinosis and airway responses due to exposure to textile dust. Lung. 1976 Dec 29;154(1):17–24. doi: 10.1007/BF02713515. [DOI] [PubMed] [Google Scholar]

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