Abstract
An investigation was carried out to determine the cause of death among 450 masons in Iceland who had been exposed to hexavalent chromium, a trace element in cement. The cohort was defined as all men born between 1905 and 1945 who had, according to the Register of Masons and Stone-cutters, finished vocational training as masons. For deaths occurring between 1951 and 1982 information was obtained from the Statistical Bureau of Iceland. Expected death rates were calculated, based on the national rates for men in the corresponding age groups. The total number of deaths from all causes was less than expected for the whole study period (81 v 85.86) but, with a 20 year latent period, 58 deaths were found against 50.57 expected; with a 30 year latent period, 38 deaths were found against 27.82 expected, which may, to a large extent, be accounted for by an excess of deaths from lung cancer. Nine deaths from lung cancer were found in the cohort, eight with 20 and 30 year latent periods compared with expected rates of 2.87, 2.19, and 1.28 respectively. The results seem to indicate that the increased number of deaths from lung cancer among the masons has a causal relation to occupational exposure.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Davies J. M. Lung cancer mortality among workers making lead chromate and zinc chromate pigments at three English factories. Br J Ind Med. 1984 May;41(2):158–169. doi: 10.1136/oem.41.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Doll R., Peto R. Mortality in relation to smoking: 20 years' observations on male British doctors. Br Med J. 1976 Dec 25;2(6051):1525–1536. doi: 10.1136/bmj.2.6051.1525. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hayes R. B., Lilienfeld A. M., Snell L. M. Mortality in chromium chemical production workers: a prospective study. Int J Epidemiol. 1979 Dec;8(4):365–374. doi: 10.1093/ije/8.4.365. [DOI] [PubMed] [Google Scholar]
- Langård S., Andersen A. a., Gylseth B. Incidence of cancer among ferrochromium and ferrosilicon workers. Br J Ind Med. 1980 May;37(2):114–120. doi: 10.1136/oem.37.2.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Polak L., Turk J. L., Frey J. R. Studies on contact hypersensitivity to chromium compounds. Prog Allergy. 1973;17:145–226. [PubMed] [Google Scholar]
- Royle H. Toxicity of chromic acid in the chromium plating industry (1). Environ Res. 1975 Aug;10(1):39–53. doi: 10.1016/0013-9351(75)90072-9. [DOI] [PubMed] [Google Scholar]
- Royle H. Toxicity of chromic acid in the chromium plating industry(2). Environ Res. 1975 Aug;10(1):141–163. doi: 10.1016/0013-9351(75)90079-1. [DOI] [PubMed] [Google Scholar]