BMP4 augments the survival of hepatocellular carcinoma (HCC) cells under hypoxia and hypoglycemia conditions by promoting the glycolysis pathway

In this article, we found some mistakes in Figure 2. The correct version is below. We would like to publish this Erratum to reflect this change. The authors express regrets for this mistake.

Figure 2.

BMP4 promotes proliferation and inhibits apoptosis of HCC cells under hypoxia and hypoglycemia. A. Hu7 and MHCC97H cells were infected with Ad-B4, Ad-GFP, Ad-siB4 and Ad-RFP respectively, and cultured with low glucose (LG) DMED + 100 μM CoCl₂, crystal violet cell viability assay and quantitative analysis of crystal violet staining were carried out at 24 h, 48 h and 72 h. “**” P < 0.01, “*” P < 0.05, Ad-B4 group vs. Ad-GFP group, “##” P < 0.01, “#” P < 0.05, Ad-siB4 group vs. Ad-RFP group. B. Hu7 and MHCC97H cells were infected with Ad-B4, Ad-GFP, Ad-siB4 and Ad-RFP respectively, and cultured with low glucose (LG) DMED + 100 μM CoCl2, WST-1 assay was done to at 0 h, 24 h, 48 h, and 72 h. “**” P < 0.01, “*” P < 0.05, Ad-B4 group vs. Ad-GFP group, “##” P < 0.01, “#” P < 0.05, Ad-siB4 group vs. Ad-RFP group. C. Hu7 and MHCC97H cells were infected with Ad-B4, Ad-GFP, Ad-siB4 and Ad-RFP respectively, and cultured with low glucose (LG) DMED + 100 μM CoCl₂, flow cytometry analysis was conducted, and the ratio of late apoptotic cells (%) was calculated at 48 h. “**” P < 0.01, “*” P < 0.05, Ad-B4 group vs. Ad-GFP group, “#” P < 0.05, Ad-siB4 group vs. Ad-RFP group.