Figure 3.

Serum inflammatory dynamics by index event. (A) Graphical representation of index event analysis: hypothetical patient #1 displays early grade 1 CRS and no infections; patient #2 displays grade early 2 CRS followed by a severe infection; patient #3 displays an early severe infection followed by grade 1 CRS. Serum procalcitonin (B), CRP (C), and IL-6 (D) levels were retrospectively assessed relative to the respective index event (severe infection: green; grade 1 CRS: gray; grade ≥2 CRS: magenta). The aggregated median values are depicted. CRP = C-reactive protein; CRS = cytokine release syndrome; IL-6 = interleukin-6.