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. 1966 Oct;23(4):302–304. doi: 10.1136/oem.23.4.302

Acute Toxicity and Skin Irritant Properties of Sulfolane

V K H Brown 1, L W Ferrigan 1, D E Stevenson 1
PMCID: PMC1008468  PMID: 5926894

Abstract

Sulfolane is a useful industrial solvent. The oral LD50 values were: rats, 1·7 to 2·7 g./kg.; mice, 1·9 to 2·5 g./kg., all deaths taking place within 24 hours. Rats showed no effects after 3·8 g./kg. had been applied to the skin. The compound did not irritate or sensitize the skins of guinea-pigs or rabbits and, undiluted, was almost without action on the eyes of rabbits.

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Selected References

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  1. Hunter C. G., Brown V. K., Ferrigan L. W. Experimental studies on skin hazard with "Versatic" 9-II acid and its monoglycidyl and vinyl esters. Br J Ind Med. 1966 Apr;23(2):137–141. doi: 10.1136/oem.23.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]

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