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. 1969 Apr;26(2):101–108. doi: 10.1136/oem.26.2.101

An investigation of allergy in byssinosis: sensitization to cotton, hemp, flax and jute antigens

V Popa 1, N Gavrilescu 1, N Preda 1, D Teculescu 1, M Plecias 1, M Cîrstea 1
PMCID: PMC1008902  PMID: 5780100

Abstract

Popa, V., Gavrilescu, N., Preda, N., Teculescu, D., Plecias, M., and Cîrstea, M. (1969).Brit. J. industr. Med.,26, 101-108. An investigation of allergy in byssinosis: sensitization to cotton, hemp, flax, and jute antigens. The authors investigated allergy to cotton, hemp, flax, and jute in 41 subjects with byssinosis. In contrast with immediate skin reactions, which were seldom observed, delayed reactions were nearly always present. The incidence of positive skin tests in byssinosis was similar to that observed in all textile workers. Inhalation tests with textile allergens were negative in all but four subjects who also had a concomitant bronchial asthma. Fifteen out of 31 subjects with byssinosis had positive inhalation tests to acetylcholine but only one of the 13 tested had a positive response to the inhalation of textile macerate. Haemagglutinating antibodies to low titres could be observed in byssinosis as well as in chronic bronchitis, in bronchial asthma, and in the general population. The significance of various types of antibodies existing in byssinosis is further discussed. The authors stress the need to standardize textile allergens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANTWEILER H. Observations about a histamine liberating substance in cotton dust. Ann Occup Hyg. 1960 Jul;2:152–156. [PubMed] [Google Scholar]
  2. BORDUAS A. G., GRABAR P. L'hemagglutination passive dans la recherche des anticorps antiprotéiques. Ann Inst Pasteur (Paris) 1953 May;84(5):903–923. [PubMed] [Google Scholar]
  3. BOUHUYS A., van DUYN, van LENNEP H. Byssinosis in flax workers. Arch Environ Health. 1961 Nov;3:499–509. doi: 10.1080/00039896.1961.10663061. [DOI] [PubMed] [Google Scholar]
  4. Bouhuys A. Response to inhaled histamine in bronchial asthma and in byssinosis. Am Rev Respir Dis. 1967 Jan;95(1):89–93. doi: 10.1164/arrd.1967.95.1.89. [DOI] [PubMed] [Google Scholar]
  5. CAYTON H. R., FURNESS G., MAITLAND H. B. Studies on cotton dust in relation to byssinosis. II. Skin tests for allergy with extracts of cotton dust. Br J Ind Med. 1952 Jul;9(3):186–196. doi: 10.1136/oem.9.3.186. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FURNESS G., MAITLAND H. B. Studies on cotton dust in relation to byssinosis. I. Bacteria and fungi in cotton dust. Br J Ind Med. 1952 Apr;9(2):138–145. doi: 10.1136/oem.9.2.138. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. GERNEZ-RIEUX C., VOISIN C., JACOB M., CORSIN L., LEFEBVRE J. [Allergological survey of 40 cotton spinning workers suffering from dyspneic disorders at work]. Poumon Coeur. 1962;18:651–657. [PubMed] [Google Scholar]
  8. MAIR A., SMITH D. H., WILSON W. A., LOCKHART W. Dust diseases in Dundee textile workers. An investigation into chronic respiratory disease in jute and flax industries. Br J Ind Med. 1960 Oct;17:272–278. doi: 10.1136/oem.17.4.272. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. MAITLAND H. B. Recherches sur le rôle de l'allergie aux poussières du coton dans la pathogénie de la byssinose. Rev Med Liege. 1956 Jun 1;11(11):323–334. [PubMed] [Google Scholar]
  10. MASSOUD A., TAYLOR G. BYSSINOSIS: ANTIBODY TO COTTON ANTIGENS IN NORMAL SUBJECTS AND IN COTTON CARD-ROOM WORKERS. Lancet. 1964 Sep 19;2(7360):607–610. doi: 10.1016/s0140-6736(64)90506-9. [DOI] [PubMed] [Google Scholar]
  11. Massoud A. A., Altounyan R. E., Howell J. B., Lane R. E. Effects of histamine aerosol in byssinotic subjects. Br J Ind Med. 1967 Jan;24(1):38–40. doi: 10.1136/oem.24.1.38. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. OUCHTERLONY O. Diffusion-in-gel methods for immunological analysis. II. Prog Allergy. 1962;6:30–154. doi: 10.1159/000313795. [DOI] [PubMed] [Google Scholar]
  13. PEPYS J. The role of human precipitins to common fungal antigens in allergic reactions. Acta Allergol Suppl (Copenh) 1960;7:108–111. [PubMed] [Google Scholar]
  14. PERNIS B., VIGLIANI E. C., CAVAGNA C., FINULLI M. The role of bacterial endotoxins in occupational diseases caused by inhaling vegetable dusts. Br J Ind Med. 1961 Apr;18:120–129. doi: 10.1136/oem.18.2.120. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Popa V., Teculescu D., Stănescu D., Gavrilescu N. The value of inhalation tests in perennial bronchial asthma. J Allergy. 1968 Sep;42(3):130–139. doi: 10.1016/0021-8707(68)90086-5. [DOI] [PubMed] [Google Scholar]
  16. SCHILLING R. S. Byssinosis in cotton and other textile workers. Lancet. 1956 Aug 18;271(6938):319–concl. doi: 10.1016/s0140-6736(56)92187-0. [DOI] [PubMed] [Google Scholar]
  17. SMITH D. H., LOCKHART W., MAIR A., WILSON W. A. Flax workers' byssinosis in East Scotland. Scott Med J. 1962 May;7:201–211. doi: 10.1177/003693306200700501. [DOI] [PubMed] [Google Scholar]
  18. Verbeke R., Tasson J., Verbeke J. Beroepsziekten en recidiverende bronchitis. Onderzoek naar de pathogenese van de byssinose. Acta Tuberc Pneumol Belg. 1964 Nov-Dec;55(6):525–534. [PubMed] [Google Scholar]
  19. Voisin C., Jacob M., Furon D., Lefebvre J. Aspects cliniques et allergologiques des manifestations asthmatiques observées chez 114 ouvriers de filatures de coton. Poumon Coeur. 1966;22(5):529–538. [PubMed] [Google Scholar]
  20. WERNER G. C. De la bronchiolite oedémateuse allergique; essai statistique sur l'asthme des poussières textiles végétales. Arch Mal Prof. 1955;16(1):27–45. [PubMed] [Google Scholar]

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