Abstract
Hocken, A. G., and Bradshaw, G. (1970).Brit. J. industr. Med.,27, 56-60. Arsine poisoning. A case of acute arsine poisoning is described, occurring in an industrial metallurgy worker. The clinical course was of associated oliguric renal failure with acute haemolytic anaemia which was self-limiting but accompanied by marked non-thrombotic phlebitis. There was minor hepatocellular damage. Skin pigmentation was disproportionate to the elevation of serum bilirubin. Transient initial pulmonary oedema was regarded as a local irritative phenomenon.
All systems underwent complete recovery. Renal function in particular was explored in all modalities, and no abnormality could be found in glomerular filtration, concentrating power or acidification 12 months after exposure. There was no proteinuria. The clinical picture was of acute tubular necrosis, although interstitial fibrosis was present and its incomplete final resolution is possible.
Contrary to the findings of other workers, no evidence was found of myocardial damage at any stage either clinically or electrocardiographically.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BERLYNE G. M., JONES J. H., HEWITT V., NILWARANGKUR S. PROTEIN LOSS IN PERITONEAL DIALYSIS. Lancet. 1964 Apr 4;1(7336):738–741. doi: 10.1016/s0140-6736(64)92849-1. [DOI] [PubMed] [Google Scholar]
- Briggs J. D., Kennedy A. C., Young L. N., Luke R. G., Gray M. Renal function after acute tubular necrosis. Br Med J. 1967 Aug 26;3(5564):513–516. doi: 10.1136/bmj.3.5564.513. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DOIG A. T. Arseniuretted hydrogen poisoning in tank cleaners. Lancet. 1958 Jul 12;2(7037):88–92. doi: 10.1016/s0140-6736(58)91258-3. [DOI] [PubMed] [Google Scholar]
- JOSEPHSON C. J., PINTO S. S., PETRONELLA S. J. Arsine: electrocardiographic changes produced in acute human poisoning. AMA Arch Ind Hyg Occup Med. 1951 Jul;4(1):43–52. [PubMed] [Google Scholar]
- MACAULAY D. B., STANLEY D. A. Arsine poisoning. Br J Ind Med. 1956 Jul;13(3):217–221. doi: 10.1136/oem.13.3.217. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Muehrcke R. C., Pirani C. L. Arsine-induced anuria. A correlative clinicopathological study with electron microscopic observations. Ann Intern Med. 1968 Apr;68(4):853–866. doi: 10.7326/0003-4819-68-4-853. [DOI] [PubMed] [Google Scholar]
- PINTO S. S., PETRONELLA S. J., JOHNS D. R., ARNOLD M. F. Arsine poisoning; a study of 13 cases. Arch Ind Hyg Occup Med. 1950 Apr;1(4):437–451. [PubMed] [Google Scholar]
- WRONG O., DAVIES H. E. The excretion of acid in renal disease. Q J Med. 1959 Apr;28(110):259–313. [PubMed] [Google Scholar]