Abstract
Butler, C. II, and Kleinerman, J. (1971). Brit. J. industr. Med., 28, 67-71. Paraquat in the rabbit. Forty rabbits received paraquat intraperitoneally in total dosages of from 2 to 100 mg/kg and in one to five separate administrations. Nine animals which received 25 mg/kg or more died within four days of administration, and the remainder were killed at intervals of up to one month. The delayed pulmonary changes produced in man and other species by paraquat were not found in any animal, despite the fact that most animals were made ill by the chemical. Atrophy of the thymus and minimal renal tubular and focal peritoneal changes were present in animals found dead or killed soon after administration, but it was difficult to explain the cause of death.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Almog C., Tal E. Death from paraquat after subcutaneous injection. Br Med J. 1967 Sep 16;3(5567):721–721. doi: 10.1136/bmj.3.5567.721. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bullivant C. M. Accidental poisoning by paraquat: Report of two cases in man. Br Med J. 1966 May 21;1(5498):1272–1273. doi: 10.1136/bmj.1.5498.1272. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Campbell S. Death from paraquat in a child. Lancet. 1968 Jan 20;1(7534):144–144. doi: 10.1016/s0140-6736(68)92754-2. [DOI] [PubMed] [Google Scholar]
- Clark D. G., McElligott T. F., Hurst E. W. The toxicity of paraquat. Br J Ind Med. 1966 Apr;23(2):126–132. doi: 10.1136/oem.23.2.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Daniel J. W., Gage J. C. Absorption and excretion of diquat and paraquat in rats. Br J Ind Med. 1966 Apr;23(2):133–136. doi: 10.1136/oem.23.2.133. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fennelly J. J., Gallagher J. T., Carroll R. T. Paraquat poisoning in a pregnant woman. Br Med J. 1968 Sep 21;3(5620):722–723. doi: 10.1136/bmj.3.5620.722. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kerr F., Patel A. R., Scott P. D., Tompsett S. L. Paraquat poisoning treated by forced diuresis. Br Med J. 1968 Aug 3;3(5613):290–291. doi: 10.1136/bmj.3.5613.290. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Manktelow B. W. The loss of pulmonary surfactant in paraquat poisoning: a model for the study of the respiratory distress syndrome. Br J Exp Pathol. 1967 Jun;48(3):366–369. [PMC free article] [PubMed] [Google Scholar]
- Matthew H., Logan A., Woodruff M. F., Heard B. Paraquat poisoning--lung transplantation. Br Med J. 1968 Sep 28;3(5621):759–763. doi: 10.1136/bmj.3.5621.759. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oreopoulos D. G., Soyannwo M. A., Sinniah R., Fenton S. S., Bruce J. H., McGeown M. G. Acute renal failure in case of Paraquat poisoning. Br Med J. 1968 Mar 23;1(5594):749–750. doi: 10.1136/bmj.1.5594.749. [DOI] [PMC free article] [PubMed] [Google Scholar]