Skip to main content
NCBI home page
British Journal of Industrial Medicine logoLink to British Journal of Industrial Medicine
. 1974 Jan;31(1):65–71. doi: 10.1136/oem.31.1.65

Bladder tumours and occupation: a coroner's notification scheme

C A Veys 1
PMCID: PMC1009545  PMID: 4821412

Abstract

Veys, C. A. (1974).British Journal of Industrial Medicine,31, 65-71. Bladder tumours and occupation: a coroner's notification scheme. The disease of bladder cancer accounted for 2 763 male and 1 107 female deaths in England and Wales during 1971. How much of this total is influenced by aetiological factors in the working environment is still largely unknown and is only now beginning to be studied.

In order to elucidate this question further, a coroner's notification scheme for all bladder tumours occuring within a defined geographical area was started in 1965. Details of all persons dying, on whose death certificate a bladder tumour was mentioned, were notified to the coroner's office within a six-year period (1965-70). A necropsy was carried out in almost all cases. A subsequent searching enquiry into the lifetime occupational history was conducted and this was then related to two industrial check-lists previously drawn up, on which the occupations listed exhibited either a true cause and effect relationship, or were merely associated in statistical terms.

The finding that about 20% of persons dying of this disease had a suspicious occupational history of exposure to a carcinogen was broadly in agreement with some other recent surveys whose methodology was different. In only one third of these cases, however, could the working environment be directly and realistically implicated.

The study supports the conclusion that the importance of occupational factors in the aetiology of bladder tumours has hitherto been underestimated.

Full text

PDF
65

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CASE R. A., HOSKER M. E., McDONALD D. B., PEARSON J. T. Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry. I. The role of aniline, benzidine, alpha-naphthylamine, and beta-naphthylamine. Br J Ind Med. 1954 Apr;11(2):75–104. doi: 10.1136/oem.11.2.75. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CASE R. A., HOSKER M. E. Tumour of the urinary bladder as an occupational disease in the rubber industry in England and Wales. Br J Prev Soc Med. 1954 Apr;8(2):39–50. doi: 10.1136/jech.8.2.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CASE R. A., PEARSON J. T. Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry. II. Further consideration of the role of aniline and of the manufacture of auramine and magenta (fuchsine) as possible causative agents. Br J Ind Med. 1954 Jul;11(3):213–216. doi: 10.1136/oem.11.3.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Case R. A. Tumours of the urinary tract as an occupational disease in several industries. Ann R Coll Surg Engl. 1966 Oct;39(4):213–235. [PMC free article] [PubMed] [Google Scholar]
  5. Clayson D. B., Cooper E. H. Cancer of the urinary tract. Adv Cancer Res. 1970;13:271–381. doi: 10.1016/s0065-230x(08)60168-2. [DOI] [PubMed] [Google Scholar]
  6. Cole P., Hoover R., Friedell G. H. Occupation and cancer of the lower urinary tract. Cancer. 1972 May;29(5):1250–1260. doi: 10.1002/1097-0142(197205)29:5<1250::aid-cncr2820290518>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  7. Cole P., Monson R. R., Haning H., Friedell G. H. Smoking and cancer f the lower urinary tract. N Engl J Med. 1971 Jan 21;284(3):129–134. doi: 10.1056/NEJM197101212840304. [DOI] [PubMed] [Google Scholar]
  8. DAVIES J. M. BLADDER TUMOURS IN THE ELECTRIC-CABLE INDUSTRY. Lancet. 1965 Jul 24;2(7404):143–146. doi: 10.1016/s0140-6736(65)90228-x. [DOI] [PubMed] [Google Scholar]
  9. DOLL R., FISHER R. E., GAMMON E. J., GUNN W., HUGHES G. O., TYRER F. H., WILSON W. MORTALITY OF GASWORKERS WITH SPECIAL REFERENCE TO CANCERS OF THE LUNG AND BLADDER, CHRONIC BRONCHITIS, AND PNEUMOCONIOSIS. Br J Ind Med. 1965 Jan;22:1–12. doi: 10.1136/oem.22.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Doll R., Vessey M. P., Beasley R. W., Buckley A. R., Fear E. C., Fisher R. E., Gammon E. J., Gunn W., Hughes G. O., Lee K. Mortality of gasworkers - final report of a prospective study. Br J Ind Med. 1972 Oct;29(4):394–406. doi: 10.1136/oem.29.4.394. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Dunham L. J., Rabson A. S., Stewart H. L., Frank A. S., Young J. L. Rates, interview, and pathology study of cancer of the urinary bladder in New Orleans, Louisiana. J Natl Cancer Inst. 1968 Sep;41(3):683–709. [PubMed] [Google Scholar]
  12. Guira A. C. Bladder carcinoma in rubber workers. J Urol. 1971 Oct;106(4):548–552. doi: 10.1016/s0022-5347(17)61338-7. [DOI] [PubMed] [Google Scholar]
  13. MELICK W. F., ESCUE H. M., NARYKA J. J., MEZERA R. A., WHEELER E. P. The first reported cases of human bladder tumors due to a new carcinogen-xenylamine. J Urol. 1955 Dec;74(6):760–766. doi: 10.1016/S0022-5347(17)67344-0. [DOI] [PubMed] [Google Scholar]
  14. SCOTT T. S. The incidence of bladder tumours in a dyestuffs factory. Br J Ind Med. 1952 Apr;9(2):127–132. doi: 10.1136/oem.9.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Staszewski J. Smoking and cancer of the urinary bladder in males in Poland. Br J Cancer. 1966 Mar;20(1):32–35. doi: 10.1038/bjc.1966.4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Veys C. A. Two epidemiological inquiries into the incidence of bladder tumors in industrial workers. J Natl Cancer Inst. 1969 Jul;43(1):219–226. [PubMed] [Google Scholar]
  17. WYNDER E. L., ONDERDONK J., MANTEL N. AN EPIDEMIOLOGICAL INVESTIGATION OF CANCER OF THE BLADDER. Cancer. 1963 Nov;16:1388–1407. doi: 10.1002/1097-0142(196311)16:11<1388::aid-cncr2820161104>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Industrial Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES