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. 2023 Apr 3;28(7):3172. doi: 10.3390/molecules28073172

Figure 2.

Figure 2

(A,B) Residual activity (%) of PfGAPDH upon incubation with 100 µM of compounds 1ad, 2ad, 3ad, and 4ad for 3 h (A) or 50 µM of compounds 2ad and 3ad for 30 min (B). All experiments were performed at 25 °C in a buffered solution containing 10 mM of TEA, 5 mM of EDTA, and 10 mM of sodium arsenate, pH 7.6. PfGAPDH was at 2 µM concentration. CTRL: activity of PfGAPDH maintained under the same conditions in the absence of inhibitors. Experiments were performed in independent triplicates. Data are shown as mean ± SD.