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. 1988 Oct;45(10):705–709. doi: 10.1136/oem.45.10.705

Gliomas and exposure to wood preservatives.

S Cordier 1, M Poisson 1, M Gerin 1, J Varin 1, F Conso 1, D Hemon 1
PMCID: PMC1009681  PMID: 3196664

Abstract

A case-referent study was undertaken to look for occupational risk factors among patients with glioma treated in a neurological hospital in Paris between 1975 and 1984. In the study group were 125 men with gliomas (aged less than or equal to 65) and 238 patients (also less than or equal to 65) admitted for non-neoplastic, non-malformative vascular diseases in the same department during the same period constituting the reference group. All diagnoses were confirmed by tomodensitometry. Information on occupational history was obtained from a postal questionnaire and from medical records. Comparison of cases and referents showed a significant excess risk among teachers (OR = 4.1) and a raised risk among wood workers (OR = 1.6). Four of nine cases of glioma who had been employed as wood workers reported that a colleague had suffered from glioma (those reports were confirmed by hospital records). None were reported among 11 referent wood workers. Using a complementary questionnaire on wood work, exposure assessment to wood preservatives and solvents showed that frequent exposure to organochlorine wood preservatives and to organic solvents occurred more often among cases than referent wood workers (p less than 0.10).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ahlbom A., Navier I. L., Norell S., Olin R., Spännare B. Nonoccupational risk indicators for astrocytomas in adults. Am J Epidemiol. 1986 Aug;124(2):334–337. doi: 10.1093/oxfordjournals.aje.a114393. [DOI] [PubMed] [Google Scholar]
  2. Dubrow R., Wegman D. H. Cancer and occupation in Massachusetts: a death certificate study. Am J Ind Med. 1984;6(3):207–230. doi: 10.1002/ajim.4700060305. [DOI] [PubMed] [Google Scholar]
  3. Englund A., Ekman G., Zabrielski L. Occupational categories among brain tumor cases recorded in the cancer registry in Sweden. Ann N Y Acad Sci. 1982;381:188–196. doi: 10.1111/j.1749-6632.1982.tb50384.x. [DOI] [PubMed] [Google Scholar]
  4. Gold E., Gordis L., Tonascia J., Szklo M. Risk factors for brain tumors in children. Am J Epidemiol. 1979 Mar;109(3):309–319. doi: 10.1093/oxfordjournals.aje.a112684. [DOI] [PubMed] [Google Scholar]
  5. Gérin M., Siemiatycki J., Kemper H., Bégin D. Obtaining occupational exposure histories in epidemiologic case-control studies. J Occup Med. 1985 Jun;27(6):420–426. [PubMed] [Google Scholar]
  6. McLaughlin J. K., Malker H. S., Blot W. J., Malker B. K., Stone B. J., Weiner J. A., Ericsson J. L., Fraumeni J. F., Jr Occupational risks for intracranial gliomas in Sweden. J Natl Cancer Inst. 1987 Feb;78(2):253–257. [PubMed] [Google Scholar]
  7. Musicco M., Filippini G., Bordo B. M., Melotto A., Morello G., Berrino F. Gliomas and occupational exposure to carcinogens: case-control study. Am J Epidemiol. 1982 Nov;116(5):782–790. doi: 10.1093/oxfordjournals.aje.a113468. [DOI] [PubMed] [Google Scholar]
  8. Pleven C. Survenue élective de glioblastomes lors de manipulation en laboratoire de recherche de dérivés de la nitrosoguanidine. Presse Med. 1984 Oct 20;13(37):2268–2268. [PubMed] [Google Scholar]
  9. Preston-Martin S., Henderson B. E., Peters J. M. Descriptive epidemiology of central nervous system neoplasms in Los Angeles County. Ann N Y Acad Sci. 1982;381:202–208. doi: 10.1111/j.1749-6632.1982.tb50386.x. [DOI] [PubMed] [Google Scholar]
  10. Stellman S. D., Garfinkel L. Cancer mortality among woodworkers. Am J Ind Med. 1984;5(5):343–357. doi: 10.1002/ajim.4700050503. [DOI] [PubMed] [Google Scholar]
  11. Thomas T. L., Fontham E. T., Norman S. A., Stemhagen A., Hoover R. N. Occupational risk factors for brain tumors. A case-referent death-certificate analysis. Scand J Work Environ Health. 1986 Apr;12(2):121–127. doi: 10.5271/sjweh.2168. [DOI] [PubMed] [Google Scholar]
  12. Unger M., Olsen J. Organochlorine compounds in the adipose tissue of deceased people with and without cancer. Environ Res. 1980 Dec;23(2):257–263. doi: 10.1016/0013-9351(80)90059-6. [DOI] [PubMed] [Google Scholar]
  13. Waldron H. A. Solvents and the brain. Br J Ind Med. 1986 Feb;43(2):73–74. doi: 10.1136/oem.43.2.73. [DOI] [PMC free article] [PubMed] [Google Scholar]

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