Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 9;28(72):e202202428. doi: 10.1002/chem.202202428

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

(a) Time course of 4‐methoxybenzoic acid conversion into 4‐hydroxybenzoic acid by CYP199A4 isoforms. (b) HPLC analysis of the amount of 4‐hydroxybenzoic acid product (RT=5.8 min) generated by the CYP199A4 isoforms over 240 minutes. (c) Time course of 4‐methylthiobenzoic acid conversion into the corresponding sulfoxide by CYP199A4 isoforms. (d) HPLC analysis of the amount of the 4‐methylsulfinylbenzoic acid product (RT=4.7 min) generated by the CYP199A4 isoforms over 240 minutes. No sulfone (sulfone RT=6.9 min) was detected. Note that in the HPLC analysis the internal standard and substrate peaks are not shown in the Figures above (see Figure S13 and S14 for further details and the full chromatograms).