Skip to main content
NCBI home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1995 Dec;54(12):942–943. doi: 10.1136/ard.54.12.942

Prostaglandin endoperoxide synthetase isoenzymes: the clinical relevance of selective inhibition.

J C Frölich 1
PMCID: PMC1010055  PMID: 8546523

Full text

PDF
942

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Flower R. J., Vane J. R. Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature. 1972 Dec 15;240(5381):410–411. doi: 10.1038/240410a0. [DOI] [PubMed] [Google Scholar]
  2. Fu J. Y., Masferrer J. L., Seibert K., Raz A., Needleman P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem. 1990 Oct 5;265(28):16737–16740. [PubMed] [Google Scholar]
  3. Gabriel S. E., Jaakkimainen L., Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs. A meta-analysis. Ann Intern Med. 1991 Nov 15;115(10):787–796. doi: 10.7326/0003-4819-115-10-787. [DOI] [PubMed] [Google Scholar]
  4. Kaufman D. W., Kelly J. P., Sheehan J. E., Laszlo A., Wiholm B. E., Alfredsson L., Koff R. S., Shapiro S. Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding. Clin Pharmacol Ther. 1993 Apr;53(4):485–494. doi: 10.1038/clpt.1993.55. [DOI] [PubMed] [Google Scholar]
  5. Klein T., Nüsing R. M., Pfeilschifter J., Ullrich V. Selective inhibition of cyclooxygenase 2. Biochem Pharmacol. 1994 Oct 18;48(8):1605–1610. doi: 10.1016/0006-2952(94)90205-4. [DOI] [PubMed] [Google Scholar]
  6. Knott I., Dieu M., Burton M., Houbion A., Remacle J., Raes M. Induction of cyclooxygenase by interleukin 1: comparative study between human synovial cells and chondrocytes. J Rheumatol. 1994 Mar;21(3):462–466. [PubMed] [Google Scholar]
  7. Kujubu D. A., Fletcher B. S., Varnum B. C., Lim R. W., Herschman H. R. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem. 1991 Jul 15;266(20):12866–12872. [PubMed] [Google Scholar]
  8. Kujubu D. A., Herschman H. R. Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J Biol Chem. 1992 Apr 25;267(12):7991–7994. [PubMed] [Google Scholar]
  9. Laneuville O., Breuer D. K., Dewitt D. L., Hla T., Funk C. D., Smith W. L. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 1994 Nov;271(2):927–934. [PubMed] [Google Scholar]
  10. Masferrer J. L., Seibert K., Zweifel B., Needleman P. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme. Proc Natl Acad Sci U S A. 1992 May 1;89(9):3917–3921. doi: 10.1073/pnas.89.9.3917. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Meade E. A., Smith W. L., DeWitt D. L. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J Biol Chem. 1993 Mar 25;268(9):6610–6614. [PubMed] [Google Scholar]
  12. Mitchell J. A., Akarasereenont P., Thiemermann C., Flower R. J., Vane J. R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693–11697. doi: 10.1073/pnas.90.24.11693. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Náray-Fejes-Tóth A., Fejes-Tóth G., Fischer C., Frölich J. C. Effect of dexamethasone on in vivo prostanoid production in the rabbit. J Clin Invest. 1984 Jul;74(1):120–123. doi: 10.1172/JCI111391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Rosenkrantz B., Náray-Fejes-Tóth A., Fejes-Tóth G., Fischer C., Sawada M., Frölich J. C. Dexamethasone effect on prostanoid formation in healthy man. Clin Sci (Lond) 1985 Jun;68(6):681–685. doi: 10.1042/cs0680681. [DOI] [PubMed] [Google Scholar]
  15. Rosenkranz B., Fischer C., Meese C. O., Frölich J. C. Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man. Br J Clin Pharmacol. 1986 Mar;21(3):309–317. doi: 10.1111/j.1365-2125.1986.tb05195.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Slater D., Berger L., Newton R., Moore G., Bennett P. The relative abundance of type 1 to type 2 cyclo-oxygenase mRNA in human amnion at term. Biochem Biophys Res Commun. 1994 Jan 14;198(1):304–308. doi: 10.1006/bbrc.1994.1043. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES