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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1996 Jul;55(7):407–410. doi: 10.1136/ard.55.7.407

Should patients with recent onset rheumatoid arthritis be offered genetic screening?

D P Symmons 1, W E Ollier 1, P Brennan 1, A J Silman 1
PMCID: PMC1010200  PMID: 8774156

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Emery P., Salmon M., Bradley H., Wordsworth P., Tunn E., Bacon P. A., Waring R. Genetically determined factors as predictors of radiological change in patients with early symmetrical arthritis. BMJ. 1992 Dec 5;305(6866):1387–1389. doi: 10.1136/bmj.305.6866.1387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Emery P., Salmon M. Early rheumatoid arthritis: time to aim for remission? Ann Rheum Dis. 1995 Dec;54(12):944–947. doi: 10.1136/ard.54.12.944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Gough A., Faint J., Salmon M., Hassell A., Wordsworth P., Pilling D., Birley A., Emery P. Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome. Arthritis Rheum. 1994 Aug;37(8):1166–1170. doi: 10.1002/art.1780370809. [DOI] [PubMed] [Google Scholar]
  4. Gregersen P. K., Silver J., Winchester R. J. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 1987 Nov;30(11):1205–1213. doi: 10.1002/art.1780301102. [DOI] [PubMed] [Google Scholar]
  5. Lanchbury J. S., Jaeger E. E., Sansom D. M., Hall M. A., Wordsworth P., Stedeford J., Bell J. I., Panayi G. S. Strong primary selection for the Dw4 subtype of DR4 accounts for the HLA-DQw7 association with Felty's syndrome. Hum Immunol. 1991 Sep;32(1):56–64. doi: 10.1016/0198-8859(91)90117-r. [DOI] [PubMed] [Google Scholar]
  6. Ollier W. E., MacGregor A. Genetic epidemiology of rheumatoid disease. Br Med Bull. 1995 Apr;51(2):267–285. doi: 10.1093/oxfordjournals.bmb.a072960. [DOI] [PubMed] [Google Scholar]
  7. Ollier W., Thomson W. Population genetics of rheumatoid arthritis. Rheum Dis Clin North Am. 1992 Nov;18(4):741–759. [PubMed] [Google Scholar]
  8. Suarez-Almazor M. E., Tao S., Moustarah F., Russell A. S., Maksymowych W. HLA-DR1, DR4, and DRB1 disease related subtypes in rheumatoid arthritis. Association with susceptibility but not severity in a city wide community based study. J Rheumatol. 1995 Nov;22(11):2027–2033. [PubMed] [Google Scholar]
  9. Symmons D. P., Barrett E. M., Bankhead C. R., Scott D. G., Silman A. J. The incidence of rheumatoid arthritis in the United Kingdom: results from the Norfolk Arthritis Register. Br J Rheumatol. 1994 Aug;33(8):735–739. doi: 10.1093/rheumatology/33.8.735. [DOI] [PubMed] [Google Scholar]
  10. Thomson W., Pepper L., Payton A., Carthy D., Scott D., Ollier W., Silman A., Symmons D. Absence of an association between HLA-DRB1*04 and rheumatoid arthritis in newly diagnosed cases from the community. Ann Rheum Dis. 1993 Jul;52(7):539–541. doi: 10.1136/ard.52.7.539. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Weyand C. M., Hicok K. C., Conn D. L., Goronzy J. J. The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann Intern Med. 1992 Nov 15;117(10):801–806. doi: 10.7326/0003-4819-117-10-801. [DOI] [PubMed] [Google Scholar]
  12. Wordsworth P., Pile K. D., Buckely J. D., Lanchbury J. S., Ollier B., Lathrop M., Bell J. I. HLA heterozygosity contributes to susceptibility to rheumatoid arthritis. Am J Hum Genet. 1992 Sep;51(3):585–591. [PMC free article] [PubMed] [Google Scholar]
  13. Young A., Jaraquemada D., Awad J., Festenstein H., Corbett M., Hay F. C., Roitt I. M. Association of HLA-DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis. Preferential relationship with HLA-Dw rather than HLA-DR specificities. Arthritis Rheum. 1984 Jan;27(1):20–25. doi: 10.1002/art.1780270104. [DOI] [PubMed] [Google Scholar]
  14. de Jongh B. M., van Romunde L. K., Valkenburg H. A., de Lange G. G., van Rood J. J. Epidemiological study of HLA and GM in rheumatoid arthritis and related symptoms in an open Dutch population. Ann Rheum Dis. 1984 Aug;43(4):613–619. doi: 10.1136/ard.43.4.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. van der Heijde D. M., van Riel P. L., Nuver-Zwart I. H., Gribnau F. W., vad de Putte L. B. Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis. Lancet. 1989 May 13;1(8646):1036–1038. doi: 10.1016/s0140-6736(89)92442-2. [DOI] [PubMed] [Google Scholar]

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