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. 1996 Jul;55(7):411–420. doi: 10.1136/ard.55.7.411

Cerebral mechanisms operating in the presence and absence of inflammatory pain.

A K Jones 1, S W Derbyshire 1
PMCID: PMC1010201  PMID: 8774157

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Selected References

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  1. Apkarian A. V., Hodge C. J. Primate spinothalamic pathways: I. A quantitative study of the cells of origin of the spinothalamic pathway. J Comp Neurol. 1989 Oct 15;288(3):447–473. doi: 10.1002/cne.902880307. [DOI] [PubMed] [Google Scholar]
  2. Apkarian A. V., Hodge C. J. Primate spinothalamic pathways: II. The cells of origin of the dorsolateral and ventral spinothalamic pathways. J Comp Neurol. 1989 Oct 15;288(3):474–492. doi: 10.1002/cne.902880308. [DOI] [PubMed] [Google Scholar]
  3. Apkarian A. V., Hodge C. J. Primate spinothalamic pathways: III. Thalamic terminations of the dorsolateral and ventral spinothalamic pathways. J Comp Neurol. 1989 Oct 15;288(3):493–511. doi: 10.1002/cne.902880309. [DOI] [PubMed] [Google Scholar]
  4. Apkarian A. V., Stea R. A., Manglos S. H., Szeverenyi N. M., King R. B., Thomas F. D. Persistent pain inhibits contralateral somatosensory cortical activity in humans. Neurosci Lett. 1992 Jun 22;140(2):141–147. doi: 10.1016/0304-3940(92)90088-o. [DOI] [PubMed] [Google Scholar]
  5. Bandura A., Cioffi D., Taylor C. B., Brouillard M. E. Perceived self-efficacy in coping with cognitive stressors and opioid activation. J Pers Soc Psychol. 1988 Sep;55(3):479–488. doi: 10.1037//0022-3514.55.3.479. [DOI] [PubMed] [Google Scholar]
  6. Barbas H., Pandya D. N. Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey. J Comp Neurol. 1989 Aug 15;286(3):353–375. doi: 10.1002/cne.902860306. [DOI] [PubMed] [Google Scholar]
  7. Bing Z., Villanueva L., Le Bars D. Ascending pathways in the spinal cord involved in the activation of subnucleus reticularis dorsalis neurons in the medulla of the rat. J Neurophysiol. 1990 Mar;63(3):424–438. doi: 10.1152/jn.1990.63.3.424. [DOI] [PubMed] [Google Scholar]
  8. Boivie J. An anatomical reinvestigation of the termination of the spinothalamic tract in the monkey. J Comp Neurol. 1979 Aug 1;186(3):343–369. doi: 10.1002/cne.901860304. [DOI] [PubMed] [Google Scholar]
  9. Bottini G., Paulesu E., Sterzi R., Warburton E., Wise R. J., Vallar G., Frackowiak R. S., Frith C. D. Modulation of conscious experience by peripheral sensory stimuli. Nature. 1995 Aug 31;376(6543):778–781. doi: 10.1038/376778a0. [DOI] [PubMed] [Google Scholar]
  10. Burton H., Jones E. G. The posterior thalamic region and its cortical projection in New World and Old World monkeys. J Comp Neurol. 1976 Jul 15;168(2):249–301. doi: 10.1002/cne.901680204. [DOI] [PubMed] [Google Scholar]
  11. Casey K. L., Minoshima S., Berger K. L., Koeppe R. A., Morrow T. J., Frey K. A. Positron emission tomographic analysis of cerebral structures activated specifically by repetitive noxious heat stimuli. J Neurophysiol. 1994 Feb;71(2):802–807. doi: 10.1152/jn.1994.71.2.802. [DOI] [PubMed] [Google Scholar]
  12. Chen A. C., Chapman C. R., Harkins S. W. Brain evoked potentials are functional correlates of induced pain in man. Pain. 1979 Jun;6(3):365–374. doi: 10.1016/0304-3959(79)90054-X. [DOI] [PubMed] [Google Scholar]
  13. Chen A. C. Human brain measures of clinical pain: a review. I. Topographic mappings. Pain. 1993 Aug;54(2):115–132. doi: 10.1016/0304-3959(93)90200-9. [DOI] [PubMed] [Google Scholar]
  14. Chudler E. H., Dong W. K., Kawakami Y. Cortical nociceptive responses and behavioral correlates in the monkey. Brain Res. 1986 Nov 5;397(1):47–60. doi: 10.1016/0006-8993(86)91368-5. [DOI] [PubMed] [Google Scholar]
  15. Craig A. D., Bushnell M. C., Zhang E. T., Blomqvist A. A thalamic nucleus specific for pain and temperature sensation. Nature. 1994 Dec 22;372(6508):770–773. doi: 10.1038/372770a0. [DOI] [PubMed] [Google Scholar]
  16. Derbyshire S. W., Jones A. K., Devani P., Friston K. J., Feinmann C., Harris M., Pearce S., Watson J. D., Frackowiak R. S. Cerebral responses to pain in patients with atypical facial pain measured by positron emission tomography. J Neurol Neurosurg Psychiatry. 1994 Oct;57(10):1166–1172. doi: 10.1136/jnnp.57.10.1166. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Devinsky O., Morrell M. J., Vogt B. A. Contributions of anterior cingulate cortex to behaviour. Brain. 1995 Feb;118(Pt 1):279–306. doi: 10.1093/brain/118.1.279. [DOI] [PubMed] [Google Scholar]
  18. Di Piero V., Ferracuti S., Sabatini U., Pantano P., Cruccu G., Lenzi G. L. A cerebral blood flow study on tonic pain activation in man. Pain. 1994 Feb;56(2):167–173. doi: 10.1016/0304-3959(94)90091-4. [DOI] [PubMed] [Google Scholar]
  19. FOLTZ E. L., WHITE L. E., Jr Pain "relief" by frontal cingulumotomy. J Neurosurg. 1962 Feb;19:89–100. doi: 10.3171/jns.1962.19.2.0089. [DOI] [PubMed] [Google Scholar]
  20. Gabriel M., Foster K., Orona E. Interaction of laminae of the cingulate cortex with the anteroventral thalamus during behavioral learning. Science. 1980 May 30;208(4447):1050–1052. doi: 10.1126/science.7375917. [DOI] [PubMed] [Google Scholar]
  21. Gabriel M., Sparenborg S., Kubota Y. Anterior and medial thalamic lesions, discriminative avoidance learning, and cingulate cortical neuronal activity in rabbits. Exp Brain Res. 1989;76(2):441–457. doi: 10.1007/BF00247901. [DOI] [PubMed] [Google Scholar]
  22. Hawley D. J., Wolfe F. Anxiety and depression in patients with rheumatoid arthritis: a prospective study of 400 patients. J Rheumatol. 1988 Jun;15(6):932–941. [PubMed] [Google Scholar]
  23. Hosobuchi Y. Subcortical electrical stimulation for control of intractable pain in humans. Report of 122 cases (1970-1984). J Neurosurg. 1986 Apr;64(4):543–553. doi: 10.3171/jns.1986.64.4.0543. [DOI] [PubMed] [Google Scholar]
  24. Hsieh J. C., Belfrage M., Stone-Elander S., Hansson P., Ingvar M. Central representation of chronic ongoing neuropathic pain studied by positron emission tomography. Pain. 1995 Nov;63(2):225–236. doi: 10.1016/0304-3959(95)00048-W. [DOI] [PubMed] [Google Scholar]
  25. Jones A. K., Brown W. D., Friston K. J., Qi L. Y., Frackowiak R. S. Cortical and subcortical localization of response to pain in man using positron emission tomography. Proc Biol Sci. 1991 Apr 22;244(1309):39–44. doi: 10.1098/rspb.1991.0048. [DOI] [PubMed] [Google Scholar]
  26. Jones A. K., Cunningham V. J., Ha-Kawa S., Fujiwara T., Luthra S. K., Silva S., Derbyshire S., Jones T. Changes in central opioid receptor binding in relation to inflammation and pain in patients with rheumatoid arthritis. Br J Rheumatol. 1994 Oct;33(10):909–916. doi: 10.1093/rheumatology/33.10.909. [DOI] [PubMed] [Google Scholar]
  27. Keefe F. J., Caldwell D. S., Martinez S., Nunley J., Beckham J., Williams D. A. Analyzing pain in rheumatoid arthritis patients. Pain coping strategies in patients who have had knee replacement surgery. Pain. 1991 Aug;46(2):153–160. doi: 10.1016/0304-3959(91)90070-E. [DOI] [PubMed] [Google Scholar]
  28. Kenshalo D. R., Jr, Isensee O. Responses of primate SI cortical neurons to noxious stimuli. J Neurophysiol. 1983 Dec;50(6):1479–1496. doi: 10.1152/jn.1983.50.6.1479. [DOI] [PubMed] [Google Scholar]
  29. Kerr F. W. The ventral spinothalamic tract and other ascending systems of the ventral funiculus of the spinal cord. J Comp Neurol. 1975 Feb 1;159(3):335–356. doi: 10.1002/cne.901590304. [DOI] [PubMed] [Google Scholar]
  30. Kievit J., Kuypers H. G. Organization of the thalamo-cortical connexions to the frontal lobe in the rhesus monkey. Exp Brain Res. 1977 Sep 28;29(3-4):299–322. doi: 10.1007/BF00236173. [DOI] [PubMed] [Google Scholar]
  31. Lin C. S., Merzenich M. M., Sur M., Kaas J. H. Connections of areas 3b and 1 of the parietal somatosensory strip with the ventroposterior nucleus in the owl monkey (Aotus trivirgatus). J Comp Neurol. 1979 May 15;185(2):355–371. doi: 10.1002/cne.901850209. [DOI] [PubMed] [Google Scholar]
  32. Lueck C. J., Zeki S., Friston K. J., Deiber M. P., Cope P., Cunningham V. J., Lammertsma A. A., Kennard C., Frackowiak R. S. The colour centre in the cerebral cortex of man. Nature. 1989 Aug 3;340(6232):386–389. doi: 10.1038/340386a0. [DOI] [PubMed] [Google Scholar]
  33. MEHLER W. R., FEFERMAN M. E., NAUTA W. J. Ascending axon degeneration following anterolateral cordotomy. An experimental study in the monkey. Brain. 1960 Dec;83:718–750. doi: 10.1093/brain/83.4.718. [DOI] [PubMed] [Google Scholar]
  34. MELZACK R., STOTLER W. A., LIVINGSTON W. K. Effects of discrete brainstem lesions in cats on perception of noxious stimulation. J Neurophysiol. 1958 Jul;21(4):353–367. doi: 10.1152/jn.1958.21.4.353. [DOI] [PubMed] [Google Scholar]
  35. McFarlane A. C., Brooks P. M. An analysis of the relationship between psychological morbidity and disease activity in rheumatoid arthritis. J Rheumatol. 1988 Jun;15(6):926–931. [PubMed] [Google Scholar]
  36. Nathan P. W. Pain. Br Med Bull. 1977 May;33(2):149–155. doi: 10.1093/oxfordjournals.bmb.a071415. [DOI] [PubMed] [Google Scholar]
  37. Omara F. O., Blakley B. R. The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. Br J Nutr. 1994 Dec;72(6):899–909. doi: 10.1079/bjn19940094. [DOI] [PubMed] [Google Scholar]
  38. Panerai A. E., Sacerdote P., Bianchi M., Brini A., Mantegazza P. Brain and spinal cord neuropeptides in adjuvant induced arthritis in rats. Life Sci. 1987 Sep 7;41(10):1297–1303. doi: 10.1016/0024-3205(87)90209-8. [DOI] [PubMed] [Google Scholar]
  39. Pardo J. V., Fox P. T., Raichle M. E. Localization of a human system for sustained attention by positron emission tomography. Nature. 1991 Jan 3;349(6304):61–64. doi: 10.1038/349061a0. [DOI] [PubMed] [Google Scholar]
  40. Porro C. A., Cavazzuti M. Spatial and temporal aspects of spinal cord and brainstem activation in the formalin pain model. Prog Neurobiol. 1993 Nov;41(5):565–607. doi: 10.1016/0301-0082(93)90044-s. [DOI] [PubMed] [Google Scholar]
  41. Posner M. I., Petersen S. E. The attention system of the human brain. Annu Rev Neurosci. 1990;13:25–42. doi: 10.1146/annurev.ne.13.030190.000325. [DOI] [PubMed] [Google Scholar]
  42. Seeger T. F., Sforzo G. A., Pert C. B., Pert A. In vivo autoradiography: visualization of stress-induced changes in opiate receptor occupancy in the rat brain. Brain Res. 1984 Jul 9;305(2):303–311. doi: 10.1016/0006-8993(84)90436-0. [DOI] [PubMed] [Google Scholar]
  43. Sherrington C. S., Laslett E. E. Observations on some spinal reflexes and the interconnection of spinal segments. J Physiol. 1903 Feb 23;29(1):58–96. doi: 10.1113/jphysiol.1903.sp000946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Shi T., Stevens R. T., Tessier J., Apkarian A. V. Spinothalamocortical inputs nonpreferentially innervate the superficial and deep cortical layers of SI. Neurosci Lett. 1993 Oct 1;160(2):209–213. doi: 10.1016/0304-3940(93)90415-h. [DOI] [PubMed] [Google Scholar]
  45. Sikes R. W., Vogt B. A. Nociceptive neurons in area 24 of rabbit cingulate cortex. J Neurophysiol. 1992 Nov;68(5):1720–1732. doi: 10.1152/jn.1992.68.5.1720. [DOI] [PubMed] [Google Scholar]
  46. Stevens R. T., London S. M., Apkarian A. V. Spinothalamocortical projections to the secondary somatosensory cortex (SII) in squirrel monkey. Brain Res. 1993 Dec 24;631(2):241–246. doi: 10.1016/0006-8993(93)91541-y. [DOI] [PubMed] [Google Scholar]
  47. Strick P. L. Light microscopic analysis of the cortical projection of the thalamic ventrolateral nucleus in the cat. Brain Res. 1973 May 30;55(1):1–24. doi: 10.1016/0006-8993(73)90485-x. [DOI] [PubMed] [Google Scholar]
  48. TALAIRACH J., TOURNOUX P., BANCAUD J. [Parietal surgery of pain]. Acta Neurochir (Wien) 1960 May 25;8:153–250. doi: 10.1007/BF01406275. [DOI] [PubMed] [Google Scholar]
  49. Talbot J. D., Marrett S., Evans A. C., Meyer E., Bushnell M. C., Duncan G. H. Multiple representations of pain in human cerebral cortex. Science. 1991 Mar 15;251(4999):1355–1358. doi: 10.1126/science.2003220. [DOI] [PubMed] [Google Scholar]
  50. Tsubokawa T., Katayama Y., Ueno Y., Moriyasu N. Evidence for involvement of the frontal cortex in pain-related cerebral events in cats: increase in local cerebral blood flow by noxious stimuli. Brain Res. 1981 Jul 27;217(1):179–185. doi: 10.1016/0006-8993(81)90197-9. [DOI] [PubMed] [Google Scholar]
  51. Vaccarino A. L., Melzack R. Analgesia produced by injection of lidocaine into the anterior cingulum bundle of the rat. Pain. 1989 Nov;39(2):213–219. doi: 10.1016/0304-3959(89)90008-0. [DOI] [PubMed] [Google Scholar]
  52. Vierck C. J., Jr, Luck M. M. Loss and recovery of reactivity to noxious stimuli in monkeys with primary spinothalamic cordotomies, followed by secondary and tertiary lesions of other cord sectors. Brain. 1979 Jun;102(2):233–248. doi: 10.1093/brain/102.2.233. [DOI] [PubMed] [Google Scholar]
  53. Vin-Christian K., Benoist J. M., Gautron M., Levante A., Guilbaud G. Further evidence for the involvement of SmI cortical neurons in nociception: modifications of their responsiveness over the early stage of a carrageenin-induced inflammation in the rat. Somatosens Mot Res. 1992;9(3):245–261. doi: 10.3109/08990229209144775. [DOI] [PubMed] [Google Scholar]
  54. Vogt B. A., Rosene D. L., Pandya D. N. Thalamic and cortical afferents differentiate anterior from posterior cingulate cortex in the monkey. Science. 1979 Apr 13;204(4389):205–207. doi: 10.1126/science.107587. [DOI] [PubMed] [Google Scholar]
  55. Woolsey C. N., Erickson T. C., Gilson W. E. Localization in somatic sensory and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation. J Neurosurg. 1979 Oct;51(4):476–506. doi: 10.3171/jns.1979.51.4.0476. [DOI] [PubMed] [Google Scholar]

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