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. 1996 Jul;55(7):486–488. doi: 10.1136/ard.55.7.486

Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.

N M Buchanan 1, E Toubi 1, M A Khamashta 1, F Lima 1, S Kerslake 1, G R Hughes 1
PMCID: PMC1010215  PMID: 8774170

Abstract

OBJECTIVE: To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS: The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome. RESULTS: HCQ was not apparently teratogenic. Lupus activity and obstetric outcome in the two groups were similar. CONCLUSION: HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.

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Selected References

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