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. 2022 Sep 21;14(2):306. doi: 10.4103/idoj.idoj_347_21

Trigeminal Trophic Syndrome

Manju Meena 1, Ashok K Khare 1, Lalit K Gupta 1,
PMCID: PMC10115313  PMID: 37089852

Trigeminal trophic syndrome (TTS) is a rare cause of facial ulceration resulting from self-manipulation of skin following peripheral or central injury to the trigeminal system. The average period between the trigeminal nerve injury and the onset of ulcer varies from several weeks to many years.[1] The syndrome is characterized by a triad of anesthesia, paresthesia, and a secondary persistent or recurrent facial ulceration. The common dermatological causes are Hansen’s disease and herpes zoster.[2,3] Timely recognition of TTS will promote its correct diagnosis and better management. The condition has been reported to be associated with Alzheimer’s disease and meningioma.[4] We describe TTS in a 70-year-old male who was presented with a persistent linear ulcer on the forehead and severe scarring involving the forehead, upper eyelid, and left nose [Figure 1], following an episode of herpes zoster affecting the ophthalmic division of the trigeminal nerve 1 year ago.

Figure 1.

Figure 1

Linear ulcer on the forehead and scarring involving the forehead upper eyelid and left side of the nose

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

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