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. 1992 Oct;49(10):728–731. doi: 10.1136/oem.49.10.728

Malignant melanoma of the skin among workers in a telecommunications industry: mortality study 1976-83.

L DeGuire 1, D Cyr 1, G Thériault 1, S Provencher 1, H Iturra 1, B W Case 1
PMCID: PMC1012149  PMID: 1419862

Abstract

An incidence study of malignant melanoma of the skin (MMS), conducted previously among the workers of four plants of a large telecommunications industry located in Montreal, Canada, showed a standardised incidence ratio of 2.7 (95% confidence interval (95% CI) 1.3-5.02) for the years 1976 to 1983. To describe more precisely the magnitude of the problem a mortality study was started among the same population (n = 9590) for the same period (1976-83). At the end of 1983, 9180 workers were alive, 261 were dead, and 149 (1.5%) were not traced. Standardised mortality ratios (SMRs) for all causes of death were surprisingly low for men (SMR = 0.57; 95% CI 0.50-0.64) and women (SMR = 0.56; 95% CI 0.37-0.82). The SMRs for major causes of death were also less than expected. These results may be explained by a pronounced selection bias (healthy worker effect) and by the short duration of follow up (eight years). For MMS, two deaths occurred among men (SMR = 2.00; 95% CI 0.24-7.22) and one among women (SMR = 4.81; 95% CI 0.12-26.78). A third man who died of MMS was miscoded as having a primary pulmonary melanoma. Including this case increased the SMR for MMS to 3.00 (95% CI 0.62-8.77; p = 0.08). Polyvinyl chloride and polychlorinated biphenyls were used in the plants and some of the workers did soldering. A planned case-control study will investigate other possible exposures at work.

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Selected References

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  1. Armstrong B. K., McNulty J. C., Levitt L. J., Williams K. A., Hobbs M. S. Mortality in gold and coal miners in Western Australia with special reference to lung cancer. Br J Ind Med. 1979 Aug;36(3):199–205. doi: 10.1136/oem.36.3.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Austin D. F., Reynolds P. J., Snyder M. A., Biggs M. W., Stubbs H. A. Malignant melanoma among employees of Lawrence Livermore National Laboratory. Lancet. 1981 Oct 3;2(8249):712–716. doi: 10.1016/s0140-6736(81)91047-3. [DOI] [PubMed] [Google Scholar]
  3. Bagwell S. P., Flynn S. D., Cox P. M., Davison J. A. Primary malignant melanoma of the lung. Am Rev Respir Dis. 1989 Jun;139(6):1543–1547. doi: 10.1164/ajrccm/139.6.1543. [DOI] [PubMed] [Google Scholar]
  4. Bahn A. K., Rosenwaike I., Hermann N., Grover P., Stellman J., O'Leary K. Letter: Melanoma after exposure to PCB's. N Engl J Med. 1976 Aug 19;295(8):450–450. doi: 10.1056/NEJM197608192950820. [DOI] [PubMed] [Google Scholar]
  5. Beral V., Robinson N. The relationship of malignant melanoma, basal and squamous skin cancers to indoor and outdoor work. Br J Cancer. 1981 Dec;44(6):886–891. doi: 10.1038/bjc.1981.288. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Blair A., Hayes H. M., Jr Cancer and other causes of death among U.S. veterinarians, 1966-1977. Int J Cancer. 1980 Feb 15;25(2):181–185. doi: 10.1002/ijc.2910250203. [DOI] [PubMed] [Google Scholar]
  7. Carpenter L. M. Some observations on the healthy worker effect. Br J Ind Med. 1987 May;44(5):289–291. doi: 10.1136/oem.44.5.289. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Costa A., Bonadonna G., Villa E., Valagussa P., Silvestrini R. Labeling index as a prognostic marker in non-Hodgkin's lymphomas. J Natl Cancer Inst. 1981 Jan;66(1):1–5. [PubMed] [Google Scholar]
  9. Costa G., Merletti F., Segnan N. A mortality cohort study in a north Italian aircraft factory. Br J Ind Med. 1989 Oct;46(10):738–743. doi: 10.1136/oem.46.10.738. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. De Guire L., Theriault G., Iturra H., Provencher S., Cyr D., Case B. W. Increased incidence of malignant melanoma of the skin in workers in a telecommunications industry. Br J Ind Med. 1988 Dec;45(12):824–828. doi: 10.1136/oem.45.12.824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Elwood J. M., Gallagher R. P., Davison J., Hill G. B. Sunburn, suntan and the risk of cutaneous malignant melanoma--The Western Canada Melanoma Study. Br J Cancer. 1985 Apr;51(4):543–549. doi: 10.1038/bjc.1985.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Elwood J. M., Gallagher R. P., Hill G. B., Pearson J. C. Cutaneous melanoma in relation to intermittent and constant sun exposure--the Western Canada Melanoma Study. Int J Cancer. 1985 Apr 15;35(4):427–433. doi: 10.1002/ijc.2910350403. [DOI] [PubMed] [Google Scholar]
  13. Elwood J. M., Hislop T. G. Solar radiation in the etiology of cutaneous malignant melanoma in Caucasians. Natl Cancer Inst Monogr. 1982;62:167–171. [PubMed] [Google Scholar]
  14. Evans R. D., Kopf A. W., Lew R. A., Rigel D. S., Bart R. S., Friedman R. J., Rivers J. K. Risk factors for the development of malignant melanoma--I: Review of case-control studies. J Dermatol Surg Oncol. 1988 Apr;14(4):393–408. doi: 10.1111/j.1524-4725.1988.tb03373.x. [DOI] [PubMed] [Google Scholar]
  15. Heldaas S. S., Langård S. L., Andersen A. Incidence of cancer among vinyl chloride and polyvinyl chloride workers. Br J Ind Med. 1984 Feb;41(1):25–30. doi: 10.1136/oem.41.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Koskela R. S., Järvinen E., Kolari P. J. Effect of cohort definition and follow-up length on occupational mortality rates. Scand J Work Environ Health. 1984 Oct;10(5):311–316. doi: 10.5271/sjweh.2328. [DOI] [PubMed] [Google Scholar]
  17. Lee J. A., Strickland D. Malignant melanoma: social status and outdoor work. Br J Cancer. 1980 May;41(5):757–763. doi: 10.1038/bjc.1980.138. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Monson R. R. Analysis of relative survival and proportional mortality. Comput Biomed Res. 1974 Aug;7(4):325–332. doi: 10.1016/0010-4809(74)90010-x. [DOI] [PubMed] [Google Scholar]
  19. Morpurgo G., Maggini M. A hypothesis on the etiology of malignant melanoma: the role of chemicals interfering with melanin synthesis. Eur J Cancer Clin Oncol. 1987 Aug;23(8):1213–1215. doi: 10.1016/0277-5379(87)90158-1. [DOI] [PubMed] [Google Scholar]
  20. Olin R., Vågerö D., Ahlbom A. Mortality experience of electrical engineers. Br J Ind Med. 1985 Mar;42(3):211–212. doi: 10.1136/oem.42.3.211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Pearce N., Checkoway H., Shy C. Time-related factors as potential confounders and effect modifiers in studies based on an occupational cohort. Scand J Work Environ Health. 1986 Apr;12(2):97–107. doi: 10.5271/sjweh.2161. [DOI] [PubMed] [Google Scholar]
  22. Storetvedt Heldaas S., Andersen A. A., Langård S. Incidence of cancer among vinyl chloride and polyvinyl chloride workers: further evidence for an association with malignant melanoma. Br J Ind Med. 1987 Apr;44(4):278–280. doi: 10.1136/oem.44.4.278. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Vågerö D., Ahlbom A., Olin R., Sahlsten S. Cancer morbidity among workers in the telecommunications industry. Br J Ind Med. 1985 Mar;42(3):191–195. doi: 10.1136/oem.42.3.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Vågerö D., Olin R. Incidence of cancer in the electronics industry: using the new Swedish Cancer Environment Registry as a screening instrument. Br J Ind Med. 1983 May;40(2):188–192. doi: 10.1136/oem.40.2.188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Vågerö D., Persson G. Risks, survival and trends of malignant melanoma among white and blue collar workers in Sweden. Soc Sci Med. 1984;19(4):475–478. doi: 10.1016/0277-9536(84)90207-7. [DOI] [PubMed] [Google Scholar]
  26. Wright W. E., Peters J. M., Mack T. M. Organic chemicals and malignant melanoma. Am J Ind Med. 1983;4(4):577–581. doi: 10.1002/ajim.4700040411. [DOI] [PubMed] [Google Scholar]

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