Nucleic Acids Research, Volume 50, Issue 10, 10 June 2022, Pages 5443–5466, https://doi.org/10.1093/nar/gkac018
In the originally published version of this manuscript, data in panels A and B of Figure 6 were mislabelled as being from the mdx-1 study while they are from the mdx-2 study.
The sentence ‘To investigate why PN-containing oligonucleotides exhibit improved activity, we quantified oligonucleotide in muscles of treated animals in the mdx-1 study’ should read ‘To investigate why PN-containing oligonucleotides exhibit improved activity, we quantified oligonucleotide in muscles of treated animals in the mdx-2 study.’
The sentence ‘One week after a single dose, we observed the highest tissue exposure for PN-containing molecules, DMD-2788 and DMD-3840’ should read ‘One week after the last dose, we observed the highest tissue exposure for PN-containing molecules, DMD-2788 and DMD-3840.’
The sentence ‘We further investigated tissue exposure by visualizing oligonucleotides in muscle sections from the same animals using ViewRNA, an in situ hybridization method used to detect oligonucleotide’ should read ‘We further investigated tissue exposure by visualizing oligonucleotides in muscle sections from the mdx-1 animals using ViewRNA, an in situ hybridization method used to detect oligonucleotide.’
These errors have now been corrected online.