Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1979 Apr;16(2):160–161. doi: 10.1136/jmg.16.2.160

Gastric adenocarcinoma due to ataxia-telangiectasia (Louis-Bar syndrome).

M A Frais
PMCID: PMC1012746  PMID: 458837

Abstract

A 26-year-old male with ataxia-telangiectasia died with a gastric adenocarcinoma. Malignancy is a recognised complication of this condition, the majority of cases being reticuloendothelial. There have been three reports of gastric adenocarcinoma associated with ataxia-telangiectasia; this, however, is the first in British published reports.

Full text

PDF
160

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Haerer A. F., Jackson J. F., Evers C. G. Ataxia-telangiectasia with gastric adenocarcinoma. JAMA. 1969 Dec 8;210(10):1884–1887. [PubMed] [Google Scholar]
  2. McFarlin D. E., Strober W., Waldmann T. A. Ataxia-telangiectasia. Medicine (Baltimore) 1972 Jul;51(4):281–314. doi: 10.1097/00005792-197207000-00002. [DOI] [PubMed] [Google Scholar]
  3. Paterson M. C., Smith B. P., Lohman P. H., Anderson A. K., Fishman L. Defective excision repair of gamma-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts. Nature. 1976 Apr 1;260(5550):444–447. doi: 10.1038/260444a0. [DOI] [PubMed] [Google Scholar]
  4. Peterson R. D., Cooper M. D., Good R. A. Lymphoid tissue abnormalities associated with ataxia-telangiectasia. Am J Med. 1966 Sep;41(3):342–359. doi: 10.1016/0002-9343(66)90080-5. [DOI] [PubMed] [Google Scholar]
  5. Swift M., Sholman L., Perry M., Chase C. Malignant neoplasms in the families of patients with ataxia-telangiectasia. Cancer Res. 1976 Jan;36(1):209–215. [PubMed] [Google Scholar]
  6. Waldmann T. A., McIntire K. R. Serum-alpha-fetoprotein levels in patients with ataxia-telangiectasia. Lancet. 1972 Nov 25;2(7787):1112–1115. doi: 10.1016/s0140-6736(72)92717-1. [DOI] [PubMed] [Google Scholar]
  7. Watanabe A., Hanazono H., Sogawa H., Takaya H. Stomach cancer of a 14-year-old boy with ataxia-telangiectasia. Tohoku J Exp Med. 1977 Feb;121(2):127–131. doi: 10.1620/tjem.121.127. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES